DPhPC-d87

1,2-Diphytanoyl-d78-sn-glycero-3-phosphocholine-d9

Catalog #0520

€1899 / 50 mg

Free worldwide shipping by FedEx/TNT of orders over €500.

  • CAS # 207131-40-6 (unlabeled)
  • Synonyms: d87-DPhPC; d87-DPhyPC; 1,2-ditetramethylhexadecanoyl-d78-sn-glycero-3-phosphocholine-d9; Diphytanoyl phosphatidylcholine-d87; 4 ME 16:0-d39 / 4 ME 16:0-d39 PC-d9; deuterated DPhPC; deuterated PC; 4 ME 16:0 PC-d87; d-DPhPC; d-DPhyPC
  • Formula: C48H9D87NO8P
  • Formula Weight: 933.8
  • Deuterium enrichment: 94-96% except 50% at alpha positions *>98%D available on request
  • Purity: 99% (mixture of PC isomers)
  • Supplied as: solid
  • Package: 5 mg – 1 g
  • Storage: -20°C
  • Stability: ≥ 2 years

Data: (1H-NMR, 13C-NMR, 31P-NMR, ESI-MS, TLC)

Citations of this product:

Barbet-Massin, E., Pell, A. J., Retel, J. S., Andreas, L. B., Jaudzems, K., Franks, W. T., … & Pintacuda, G. (2014). Rapid proton-detected NMR assignment for proteins with fast magic angle spinning. Journal of the American Chemical Society, 136(35), 12489-12497.

Andreas, L. B., Reese, M., Eddy, M. T., Gelev, V., Ni, Q. Z., Miller, E. A., … & Griffin, R. G. (2015). Structure and mechanism of the influenza A M218–60 dimer of dimers. Journal of the American Chemical Society, 137(47), 14877-14886.

Nimerovsky, E., Movellan, K. T., Zhang, X. C., Forster, M. C., Najbauer, E., Xue, K., … & Andreas, L. B. (2021). Proton detected solid-state NMR of membrane proteins at 28 Tesla (1.2 GHz) and 100 kHz magic-angle spinning. Biomolecules, 11(5), 752.

Stampolaki, Μ., Hoffmann, A., Tekwani, K., Georgiou, K., Tzitzoglaki, C., Ma, C., … & Kolocouris, A. (2023). A Study of the Activity of Adamantyl Amines against Mutant Influenza A M2 Channels Identified a Polycyclic Cage Amine Triple Blocker, Explored by Molecular Dynamics Simulations and Solid‐State NMR. ChemMedChem, 18(16), e202300182.

Movellan, K. T., Wegstroth, M., Overkamp, K., Leonov, A., Becker, S., & Andreas, L. B. (2023). Real-time tracking of drug binding to influenza A M2 reveals a high energy barrier. Journal of Structural Biology: X, 8, 100090.

Stampolaki, M., Varkey, A., Nimerovsky, E., Leonov, A., & Becker, S. (2024). Seeing double: the persistent dimer-of-dimers structure of drug resistant influenza A M2.