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L-α-GPC-d9
sn-Glycero-3-phosphocholine-d9
Catalog #0801
CAS # 28319-77-9 (unlabeled)
CAS # 2260669-07-4 (labeled)
Synonyms: d9-GPC; Choline
alfoscerate-d9; deuterated GPC;
d-GPC;
Glycerophosphorylcholine-d9; Alpha
GPC-d9; d-alpha GPC; Deuterated
Glycerophosphocholine;
L- alpha-Glycerophosphocholine-d9;
0:0 PC-d9
Formula:C8H11D9NO6P
Formula Weight: 266.3
Deuterium enrichment: 99%
Purity: 99%
Supplied as: solid
Hygroscopic!
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR; 31P-NMR, ESI-MS, TLC)
DH6PC-d9
1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d9
Catalog #06001
CAS # 34506-67-7 (unlabeled)
Synonyms: d9-DH6PC; d9-D6PC;
d-DC6PC; d-DH6PC; d-D6PC;
1,2-Dicaproyl-sn-glycero-3-phosphocholine-d9;
Dicaproyl phosphatidylcholine-d9; 6:0-
PC-d9; deuterated DH6PC; deuterated D6PC;
deuterated DC6PC; deuterated PC; deuterated DHPC;
L-1,2-Dihexanoyllecithin-d9;
d9-DHPC; d-DHPC
Formula:C20H31D9NO8P
Formula Weight: 462.6
Deuterium enrichment: 99%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DH6PC-d22
1,2-Dihexanoyl-d22-sn-glycero-3-phosphocholine
Catalog #0601
CAS # 34506-67-7 (unlabeled)
CAS # 328946-18-5 (labeled)
Synonyms: d22-DH6PC; d22-D6PC;
d-DC6PC; d-DH6PC; d-D6PC;
d-DC6PC
1,2-Dicaproyl-d22-sn-glycero-3-phosphocholine;
Dicaproyl phosphatidylcholine-d22;
6:0-d11 / 6:0-d11 PC; 6:0
PC-d22; deuterated DH6PC; deuterated
D6PC;
deuterated DC6PC; deuterated PC; deuterated DHPC;
L-1,2-Dihexanoyllecithin-d22;
d22-DHPC; d-DHPC
Formula:C20H18D22NO8P
Formula Weight: 475.6
Deuterium enrichment: ≥ 98% except 60-80% on alpha
positions
;99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, ESI-MS, TLC)
Citations of this product:
Piai, A., Fu, Q., Cai, Y., Ghantous, F., Xiao, T., Shaik, M. M., ... & Chou, J. J. (2020). Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein. Nature communications, 11(1), 2317.Bugge, K., Papaleo, E., Haxholm, G. W., Hopper, J. T., Robinson, C. V., Olsen, J. G., ... & Kragelund, B. B. (2016). A combined computational and structural model of the full-length human prolactin receptor. Nature communications, 7(1), 11578.
DH6PC-d31
1,2-Dihexanoyl-d22-sn-glycero-3-phosphocholine-d9
Catalog #0623
CAS # 34506-67-7 (unlabeled)
Synonyms: d31-DH6PC; d31-D6PC;
d-DC6PC; d-DH6PC; d-D6PC;
1,2-Dicaproyl-d22-sn-glycero-3-phosphocholine-d9;
Dicaproyl phosphatidylcholine-d31;
6:0-d11 / 6:0-d11
PC-d9; 6:0 PC-d31;
deuterated DH6PC; deuterated D6PC; deuterated DC6PC;
deuterated PC;
deuterated DHPC;
L-1,2-Dihexanoyllecithin-d31;
d31-DHPC; d-DHPC
Formula:C20H9D31NO8P
Formula Weight: 484.7
Deuterium enrichment: ≥ 98% except 60-80% on alpha
positions
;99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Citations of this product:
Bugge, K., Papaleo, E., Haxholm, G. W., Hopper, J. T., Robinson, C. V., Olsen, J. G., ... & Kragelund, B. B. (2016). A combined computational and structural model of the full-length human prolactin receptor. Nature communications, 7(1), 11578.
DH7PC-d9
1,2-Diheptanoyl-sn-glycero-3-phosphocholine-d9
Catalog # 1723
CAS # 39036-04-9 (unlabeled)
Synonyms: d9-Diheptanoyllecithin;
d9-DH7PC;
1,2-dienanthioyl-sn-glycero-3-phosphocholine-d9;
Dienanthioyl phosphatidylcholine-d9;
7:0 PC-d9;
Deuterated DH7PC; Deuterated PC; Deuterated
D7PC;
D7PC-d9
Formula:C22H35D9NO8P
Formula Weight: 490.6
Deuterium enrichment: 99%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DH7PC-d26
1,2-Diheptanoyl-d26-sn-glycero-3-phosphocholine
Catalog # 0701
CAS # 39036-04-9 (unlabeled)
Synonyms: d26-Diheptanoyllecithin;
1,2-dienanthioyl-d26-sn-glycero-3-phosphocholine;
Dienanthioyl phosphatidylcholine-d26;
7:0-d13 / 7:0-d13 PC; 7:0 PC-d26;
Deuterated DH7PC; d-DH7PC; d26-DH7PC;
Deuterated PC; Deuterated D7PC;
d26-D7PC; d-D7PC; Deuterated DC7PC;
d-DC7PC; d26-DC7PC; Deuterated DHPC;
d-DHPC; d26-DHPC
Formula:
C22H18D26NO8P
Formula Weight: 507.7
Deuterium enrichment: ≥ 98% on all heptanoic
acid positions, except 60-80%D on alpha
;>99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (TLC, ESI-MS, 1H-NMR, 31P-NMR)
Citations of this product:
Mohamadi, M., Goricanec, D., Wagner, G., & Hagn, F. (2023). NMR sample optimization and backbone assignment of a stabilized neurotensin receptor. Journal of structural biology, 215(2), 107970.O’Brien, E. S., Lin, D. W., Fuglestad, B., Stetz, M. A., Gosse, T., Tommos, C., & Wand, A. J. (2018). Improving yields of deuterated, methyl labeled protein by growing in H 2 O. Journal of biomolecular NMR, 71, 263-273.
DH7PC-d35
1,2-Diheptanoyl-d26-sn-glycero-3-phosphocholine-d9
Catalog # 0723
CAS # 39036-04-9 (unlabeled)
Synonyms: d35-Diheptanoyllecithin;
1,2-dienanthioyl-d26-sn-glycero-3-phosphocholine-d9;
Dienanthioyl phosphatidylcholine-d35;
7:0-d13 / 7:0-d13 PC -
d9; 7:0 PC-d35; Deuterated
DH7PC;
d-DH7PC; d35-DH7PC; Deuterated PC;
Deuterated D7PC;
d35-D7PC; d-D7PC; Deuterated DC7PC;
d-DC7PC; d35-DC7PC; Deuterated DHPC;
d-DHPC; d35-DHPC
Formula:
C22H9D35NO8P
Formula Weight: 516.8
Deuterium enrichment: ≥ 98% on the choline and
all heptanoic acid positions, except 50-70%D on
alpha
;>99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DLPC-d9
1,2-Dilauroyl-sn-glycero-3-phosphocholine-d9
Catalog #1571
CAS # 18194-25-7 (unlabeled)
Synonyms: d9-DLPC;
1,2-Didodecanoyl-sn-glycero-3-phosphocholine-d9;
Dilauroyl phosphatidylcholine-d9;
12:0 / 12:0 PC-d9;
Deuterated DLPC; Deuterated PC
Formula:C32H55D9NO8P
Formula Weight: 630.9
Deuterium enrichment: 99%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: 2 years
DLPC-d46
1,2-Dilauroyl-d46-sn-glycero-3-phosphocholine
Catalog #0571
CAS # 18194-25-7 (unlabeled)
Synonyms: d46-DLPC;
1,2-didodecanoyl-d46-sn-glycero-3-phosphocholine;
d46 -Dilauroyl phosphatidylcholine;
12:0-d23 / 12:0-d23
PC;
D-DLPC; Deuterated DLPC; Deuterated PC
Formula:C32H18D46NO8P
Formula Weight: 668.1
Deuterium enrichment: 98% except 60-80% on
the alpha positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DLPC-d55
1,2-Dilauroyl-d46-sn-glycero-3-phosphocholine-d9
Catalog #0572
CAS # 18194-25-7 (unlabeled)
Synonyms: d55-DLPC;
1,2-Didodecanoyl-d46-sn-glycero-3-phosphocholine-d9;
Dilauroyl
phosphatidylcholine-d55;
12:0-d23 / 12:0-d23
PC-d9; Deuterated DLPC;
D-DLPC; Deuterated PC
Formula:C32H9D55NO8P
Formula Weight: 677.2
Deuterium enrichment: 98% except 60-80% on
the alpha positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data
1H-NMR, 31P-NMR, ESI-MS, TLC
DMPC-d9
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d9
Catalog #1516
CAS # 18194-24-6 (unlabeled)
CAS # 71479-88-4 (labeled)
Synonyms: d9-DMPC;
1,2-ditetradecanoy-sn-glycero-3-phosphocholine-d9;
Dimyristoyl
phosphatidylcholine-d9; 14:0
/ 14:0 PC-d9; deuterated
DMPC;
deuterated PC; d-DMPC; 14:0
PC-d9
Formula:C36H63D9NO8P
Formula Weight: 687
Deuterium enrichment: 99%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
1-d27-DMPC
1-Myristoyl-d27-2-myristoyl-sn-glycero-3-phosphocholine
Catalog #1302
CAS # 18194-24-6 (unlabeled)
CAS # 185906-02-9 (labeled)
Synonyms: d27-DMPC;
1-tetradecanoyl-d27-2-tetradecanoyl-sn-glycero-3-phosphocholine;
dimyristoyl
phosphatidylcholine-d27;
14:0-d27 / 14:0 PC;
deuterated DMPC;
deuterated PC; d-DMPC; 14:0
PC-d27
Formula:C36H45D27NO8P
Formula Weight: 705.1
Deuterium enrichment: 98% except 60-80%
on the alpha positions
Contains < 10% of the 2-d27-DMPC
isomer
Purity: 99% (both isomers)
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: 1H-NMR ; 13C-NMR ; 31P-NMR (CDCl3)
2-d27-DMPC
1-Myristoyl-2-myristoyl-d27-sn-glycero-3-phosphocholine
Catalog #1303
CAS # 18194-24-6 (unlabeled)
CAS # 185906-03-0 (labeled)
Synonyms: DMPC-2-d27;
1-tetradecanoyl-2-tetradecanoyl-d27-sn-glycero-3-phosphocholine;
Dimyristoyl
phosphatidylcholine-2-d27;
14:0 / 14:0-d27 PC;
deuterated DMPC;
deuterated PC; d-DMPC; 14:0
PC-d27
Formula:C36H45D27NO8P
Formula Weight: 705.1
Deuterium enrichment: 98% except 60-80%
on the alpha positions
Contains < 10% of the 1-d27-DMPC
isomer
Purity: 99% (both isomers)
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DMPC-d54
1,2-Dimyristoyl-d54-sn-glycero-3-phosphocholine
Catalog #0501
CAS # 18194-24-6 (unlabeled)
CAS # 78415-49-3 (labeled)
Synonyms: d54-DMPC;
1,2-Ditetradecanoyl-d54-sn-glycero-3-phosphocholine;
Dimyristoyl
phosphatidylcholine-d54;
14:0-d27 /
14:0-d27 PC; Deuterated DMPC;
Deuterated PC; d-DMPC; 14:0
PC-d54
Formula:C36H18D54NO8P
Formula Weight: 732.3
Deuterium enrichment: >98% except 60-80%
on the alpha positions
* >99%D available on request
Purity: 99% (both isomers)
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, TLC, ESI-MS)
Citations of this product:
Hagn, F., Etzkorn, M., Raschle, T., & Wagner, G. (2013). Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins. Journal of the American Chemical Society, 135(5), 1919-1925.Hagn, F., & Wagner, G. (2015). Structure refinement and membrane positioning of selectively labeled OmpX in phospholipid nanodiscs. Journal of biomolecular NMR, 61, 249-260.
Bibow, S., Polyhach, Y., Eichmann, C., Chi, C. N., Kowal, J., Albiez, S., ... & Riek, R. (2017). Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein AI. Nature structural & molecular biology, 24(2), 187-193.
Hagn, F., Nasr, M. L., & Wagner, G. (2018). Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR. Nature protocols, 13(1), 79-98.
Bibow, S. (2019). Opportunities and challenges of backbone, sidechain, and RDC experiments to study membrane protein dynamics in a detergent-free lipid environment using solution state NMR. Frontiers in molecular biosciences, 6, 103.
Schuster, M., Deluigi, M., Pantić, M., Vacca, S., Baumann, C., Scott, D. J., ... & Zerbe, O. (2020). Optimizing the α1B-adrenergic receptor for solution NMR studies. Biochimica et Biophysica Acta (BBA)-Biomembranes, 1862(10), 183354.
Piai, A., Fu, Q., Cai, Y., Ghantous, F., Xiao, T., Shaik, M. M., ... & Chou, J. J. (2020). Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein. Nature communications, 11(1), 2317.
Bibow, S., Böhm, R., Modaresi, S. M., & Hiller, S. (2020). Detergent titration as an efficient method for NMR resonance assignments of membrane proteins in lipid–bilayer nanodiscs. Analytical chemistry, 92(11), 7786-7793.
Gaussmann, S., Gopalswamy, M., Eberhardt, M., Reuter, M., Zou, P., Schliebs, W., ... & Sattler, M. (2021). Membrane interactions of the peroxisomal proteins PEX5 and PEX14. Frontiers in Cell and Developmental Biology, 9, 651449.
Daniilidis, M., Brandl, M. J., & Hagn, F. (2022). The advanced properties of circularized MSP nanodiscs facilitate high-resolution NMR studies of membrane proteins. Journal of Molecular Biology, 434(24), 167861.
DMPC-d63
1,2-Dimyristoyl-d54-sn-glycero-3-phosphocholine-d9
Catalog #0554
CAS # 18194-24-6 (unlabeled)
CAS # 326495-30-1 (labeled)
Synonyms: d63-DMPC;
1,2-Ditetradecanoyl-d54-sn-glycero-3-phosphocholine-d9;
Dimyristoyl
phosphatidylcholine-d63;
14:0-d27 /
14:0-d27 PC-d9;
Deuterated DMPC; Deuterated PC; d-DMPC;
14:0-d63
Formula:C36H9D63NO8P
Formula Weight: 741.3
Deuterium enrichment: 98% except 60-80%
on the alpha positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (TLC, ESI-MS, 1H-NMR, 31P-NMR)
DPPC-d9
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine-d9
Catalog #1509
CAS # 63-89-8 (unlabeled)
CAS # 77165-56-1 (labeled)
Synonyms: d9-DPPC;
1,2-dihexadecanoyl-sn-glycero-3-phosphocholine-d9;
Dipalmitoyl
phosphatidylcholine-d9; 16:0
/ 16:0 PC-d9; deuterated
DPPC;
deuterated PC; d-DPPC 16:0 PC -
d9
Formula:
C40H71D9NO8P
Formula Weight: 743.1
Deuterium enrichment: 99%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DPPC-1-d31
1-palmitoyl-d31-2-palmitoyl-1-sn-glycero-3-phosphocholine
Catalog #1510
CAS # 63-89-8 (unlabeled)
CAS # 69285-95-6 (labeled)
Synonyms: DPPC-1-d31;
1-hexadecanoyl-d31-2-hexadecanoyl-sn-glycero-3-phosphocholine;
Dipalmitoyl
phosphatidylcholine-1-d31;
16:0-d31 / 16:0 PC;
deuterated DPPC; deuterated PC; d-DPPC;
16:0 PC - d31
Formula:
C40H49D31NO8P
Formula Weight: 765.2
Deuterium enrichment: ≥ 97% except
60-80% on the alpha positions
* > 99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DPPC-2-d31
1-Palmitoyl-2-Palmitoyl-d31-sn-glycero-3-phosphocholine
Catalog #1513
CAS # 63-89-8 (unlabeled)
CAS # 56952-02-4 (labeled)
Synonyms: DPPC-2-d31;
1-hexadecanoyl-2-hexadecanoyl-d31-sn-glycero-3-phosphocholine;
Dipalmitoyl
phosphatidylcholine-2-d31;
16:0 / 16:0-d31 PC;
deuterated DPPC;
deuterated PC; d-DPPC; 16:0 PC -
d31
Formula:
C40H49D31NO8P
Formula Weight: 765.2
Deuterium enrichment: ≥ 97% except
60-80% on the alpha positions
* > 99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DPPC-d62
1,2-Dipalmitoyl-d62-sn-glycero-3-phosphocholine
Catalog #0517
CAS # 63-89-8 (unlabeled)
CAS # 25582-63-2 (labeled)
Synonyms: d62-DPPC;
1,2-dihexadecanoyl-d62-sn-glycero-3-phosphocholine;
Dipalmitoyl
phosphatidylcholine-d62;
16:0-d31 /
16:0-d31 PC;
deuterated DPPC; deuterated PC; d-DPPC;
16:0 PC - d62
Formula:
C40H18D62NO8P
Formula Weight: 796.4
Deuterium enrichment: ≥ 97% except
60-80% on the alpha positions
* > 99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, TLC, ESI-MS)
DPPC-d71
1,2-Dipalmitoyl-d62-sn-glycero-3-phosphocholine-d9
Catalog #1610
CAS # 63-89-8 (unlabeled)
CAS # 474943-49-2 (labeled)
Synonyms: d71-DPPC;
1,2-Dihexadecanoyl-d62-sn-glycero-3-phosphocholine-d9;
Dipalmitoyl
phosphatidylcholine-d71;
16:0-d31 /
16:0-d31 PC-d9;
deuterated DPPC; deuterated PC; d-DPPC;
16:0 PC - d71
Formula:
C40H9D71NO8P
Formula Weight: 805.5
Deuterium enrichment: ≥ 97% except
60-80% on the alpha positions
* > 99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DSPC-d9
1,2-Distearoyl-sn-glycero-3-phosphocholine-d9
Catalog #0509
CAS # 816-94-4 (unlabeled)
CAS # 326495-36-7 (labeled)
Synonyms: d9-DSPC;
1,2-dioctadecanoyl-sn-glycero-3-phosphocholine-d9;
Distearoyl
phosphatidylcholine-d9; 18:0
PC-d9; deuterated DSPC;
deuterated PC; d-DSPC
Formula:
C44H79D9NO8P
Formula Weight: 799.2
Deuterium enrichment: 99%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
1-d35-DSPC
1-Stearoyl-d35-2-stearoyl-sn-glycero-3-phosphocholine
Catalog #1512
CAS # 816-94-4 (unlabeled)
CAS # 327178-89-2 (labeled)
Synonyms: d35-DSPC;
DSPC-1-d35;
1-Octadecanoyl-d35-2-octadecanoyl-sn-glycero-3-phosphocholine;
Distearoyl
phosphatidylcholine-1-d35;
Distearoyl
phosphatidylcholine-d35;
18:0-d35 / 18:0 PC;
deuterated DSPC; deuterated PC; d-DSPC;
18:0 PC-d35
Formula:
C44H53D35NO8P
Formula Weight: 825.4
Deuterium enrichment: ≥ 97% except
60-80% on the alpha positions
* Enrichment > 99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
2-d35-DSPC
1-Stearoyl-2-stearoyl-d35-sn-glycero-3-phosphocholine
Catalog #1515
CAS # 816-94-4 (unlabeled)
CAS # 327178-88-1 (labeled)
Synonyms: d35-DSPC;
DSPC-2-d35;
1-Octadecanoyl-2-octadecanoyl-d35-sn-glycero-3-phosphocholine;
Distearoyl
phosphatidylcholine-2-d35;
Distearoyl
phosphatidylcholine-d35;
18:0 / 18:0-d35 PC;
deuterated DSPC; deuterated PC; d-DSPC;
18:0 PC-d35
Formula:
C44H53D35NO8P
Formula Weight: 825.4
Deuterium enrichment: ≥ 97% except
60-80% on the alpha positions
* Enrichment > 99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DSPC-d70
1,2-Distearoyl-d70-sn-glycero-3-phosphocholine
Catalog #0570
CAS # 816-94-4 (unlabeled)
CAS # 56952-01-3 (labeled)
Synonyms: d70-DSPC;
1,2-Dioctadecanoyl-d70-sn-glycero-3-phosphocholine;
Distearoyl
phosphatidylcholine-d70;
18:0-d35 /
18:0-d35 PC; deuterated DSPC;
d-DSPC; deuterated PC; 18:0
PC-d70
Formula:
C44H18D70NO8P
Formula Weight: 860.6
Deuterium enrichment: ≥ 97% except
60-80% on the alpha positions
* Enrichment > 99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, TLC, ESI-MS)
DSPC-d79
1,2-Distearoyl-d70-sn-glycero-3-phosphocholine-d9
Catalog #1579
CAS # 816-94-4 (unlabeled)
CAS # 326495-39-0 (labeled)
Synonyms: d79-DSPC;
1,2-dioctadecanoyl-d70-sn-glycero-3-phosphocholine-d9;
Distearoyl
phosphatidylcholine-d79;
18:0-d35 /
18:0-d35 PC-d9;
deuterated DSPC; deuterated PC; d-DSPC;
18:0 PC - d79
Formula:
C44H9D79NO8P
Formula Weight: 869.6
Deuterium enrichment: ≥ 97% except
60-80% on the alpha positions
* > 99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DPhPC-d78
1,2-Diphytanoyl-d78-sn-glycero-3-phosphocholine
Catalog #05201
CAS # 207131-40-6 (unlabeled)
Synonyms: d78-DPhPC;
1,2-ditetramethylhexadecanoyl-d78-sn-glycero-3-phosphocholine;
Diphytanoyl
phosphatidylcholine-d78;
4 ME 16:0-d39 / 4 ME
16:0-d39 PC; deuterated
DPhPC;
deuterated PC;
4 ME 16:0 PC-d78; d-DPhPC;
d78-DPhyPC; d-DPhyPC
Formula:
C48H18D78NO8P
Formula Weight: 924.7
Deuterium enrichment: 94-96% except 50%
at
alpha positions
*>98%D available on request
Purity: 98% (mixture of phytanic acid
isomers)
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Citations of this product:
Barbet-Massin, E., Pell, A. J., Retel, J. S., Andreas, L. B., Jaudzems, K., Franks, W. T., ... & Pintacuda, G. (2014). Rapid proton-detected NMR assignment for proteins with fast magic angle spinning. Journal of the American Chemical Society, 136(35), 12489-12497.Andreas, L. B., Reese, M., Eddy, M. T., Gelev, V., Ni, Q. Z., Miller, E. A., ... & Griffin, R. G. (2015). Structure and mechanism of the influenza A M218–60 dimer of dimers. Journal of the American Chemical Society, 137(47), 14877-14886.
Nimerovsky, E., Movellan, K. T., Zhang, X. C., Forster, M. C., Najbauer, E., Xue, K., ... & Andreas, L. B. (2021). Proton detected solid-state NMR of membrane proteins at 28 Tesla (1.2 GHz) and 100 kHz magic-angle spinning. Biomolecules, 11(5), 752.
Stampolaki, Μ., Hoffmann, A., Tekwani, K., Georgiou, K., Tzitzoglaki, C., Ma, C., ... & Kolocouris, A. (2023). A Study of the Activity of Adamantyl Amines against Mutant Influenza A M2 Channels Identified a Polycyclic Cage Amine Triple Blocker, Explored by Molecular Dynamics Simulations and Solid‐State NMR. ChemMedChem, 18(16), e202300182.
Movellan, K. T., Wegstroth, M., Overkamp, K., Leonov, A., Becker, S., & Andreas, L. B. (2023). Real-time tracking of drug binding to influenza A M2 reveals a high energy barrier. Journal of Structural Biology: X, 8, 100090.
Stampolaki, M., Varkey, A., Nimerovsky, E., Leonov, A., & Becker, S. (2024). Seeing double: the persistent dimer-of-dimers structure of drug resistant influenza A M2.
DPhPC-d87
1,2-Diphytanoyl-d78-sn-glycero-3-phosphocholine-d9
Catalog #0520
CAS # 207131-40-6 (unlabeled)
Synonyms: d87-DPhPC;
d87-DPhyPC;
1,2-ditetramethylhexadecanoyl-d78-sn-glycero-3-phosphocholine-d9;
Diphytanoyl
phosphatidylcholine-d87; 4 ME
16:0-d39 / 4 ME
16:0-d39 PC-d9;
deuterated DPhPC;
deuterated PC; 4 ME 16:0
PC-d87;
d-DPhPC; d-DPhyPC
Formula:
C48H9D87NO8P
Formula Weight: 933.8
Deuterium enrichment: 94-96% except 50%
at
alpha positions
*>98%D available on request
Purity: 99% (mixture of PC isomers)
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR, 13C-NMR, 31P-NMR, ESI-MS, TLC)
Citations of this product:
Barbet-Massin, E., Pell, A. J., Retel, J. S., Andreas, L. B., Jaudzems, K., Franks, W. T., ... & Pintacuda, G. (2014). Rapid proton-detected NMR assignment for proteins with fast magic angle spinning. Journal of the American Chemical Society, 136(35), 12489-12497.Andreas, L. B., Reese, M., Eddy, M. T., Gelev, V., Ni, Q. Z., Miller, E. A., ... & Griffin, R. G. (2015). Structure and mechanism of the influenza A M218–60 dimer of dimers. Journal of the American Chemical Society, 137(47), 14877-14886.
Nimerovsky, E., Movellan, K. T., Zhang, X. C., Forster, M. C., Najbauer, E., Xue, K., ... & Andreas, L. B. (2021). Proton detected solid-state NMR of membrane proteins at 28 Tesla (1.2 GHz) and 100 kHz magic-angle spinning. Biomolecules, 11(5), 752.
Stampolaki, Μ., Hoffmann, A., Tekwani, K., Georgiou, K., Tzitzoglaki, C., Ma, C., ... & Kolocouris, A. (2023). A Study of the Activity of Adamantyl Amines against Mutant Influenza A M2 Channels Identified a Polycyclic Cage Amine Triple Blocker, Explored by Molecular Dynamics Simulations and Solid‐State NMR. ChemMedChem, 18(16), e202300182.
Movellan, K. T., Wegstroth, M., Overkamp, K., Leonov, A., Becker, S., & Andreas, L. B. (2023). Real-time tracking of drug binding to influenza A M2 reveals a high energy barrier. Journal of Structural Biology: X, 8, 100090.
Stampolaki, M., Varkey, A., Nimerovsky, E., Leonov, A., & Becker, S. (2024). Seeing double: the persistent dimer-of-dimers structure of drug resistant influenza A M2.
POPC-d9
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine-d9
Catalog #1555
CAS # 26853-31-6 (unlabeled)
Synonyms: d9-POPC;
1-hexadecanoyl-2-octadecenoyl-sn-glycero-3-phosphocholine-d9;
Palmitoyl oleoyl
phosphatidylcholine-d9; 16:0
/ 18:1 PC-d9; deuterated
POPC;
deuterated PC
Formula:C42H73D9NO8P
Formula Weight: 769.1
Deuterium enrichment: 99%
Purity: 99%
Supplied as: solid
Storage: -20°C under argon
Stability: ≥ 2 years
POPC-d62
1-Palmitoyl-d31-2-oleoyl-d31-sn-glycero-3-phosphocholine
Catalog #1501
CAS # 26853-31-6 (unlabeled)
Synonyms: d62-POPC;
1-hexadecanoyl-d31-2-octadecenoyl-d31-sn-glycero-3-phosphocholine;
Palmitoyl oleoyl
phosphatidylcholine-d62;
16:0-d31 /
18:1-d31 PC;
deuterated POPC; deuterated PC; d-POPC;
16:0/18:1 PC - d62
Formula:C42H20D62NO8P
Formula Weight: 822.5
Deuterium enrichment: 96-99% except
60-80% on the alpha positions and
natural abundance at the vinyl
positions
Purity: 99%
Supplied as: solid
Storage: -20°C under argon
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, TLC, ESI-MS)
1-d31-DOPC
1-Oleoyl-d31-2-oleoyl-sn-glycero-3-phosphocholine
Catalog #1157
CAS # 4235-95-4 (unlabeled)
Synonyms: DOPC-d31;
1-octadecenoyl-d31-2-octadecenoyl-sn-glycero-3-phosphocholine;
Dioleoyl
phosphatidylcholine-d31;
18:1-d31 / 18:1 PC;
deuterated DOPC;
deuterated PC; d-DOPC; Dioleoyl
lecithin-d31; 18:1 (Cis)
PC-d31
Formula:C44H53D31NO8P
Formula Weight: 817.3
Deuterium enrichment: 96-99% except
60-80% on the alpha positions
Contains < 10% of the
2-d31 isomer
Purity: 99%
Supplied as: solid
Storage: -20°C under argon
Stability: ≥ 2 years
2-d31-DOPC
1-oleoyl-2-oleoyl-d31-sn-glycero-3-phosphocholine
Catalog #1158
CAS # 4235-95-4 (unlabeled)
Synonyms: DOPC-d31;
1-octadecenoyl-2-octadecenoyl-d31-sn-glycero-3-phosphocholine;
Dioleoyl
phosphatidylcholine-d31; 18:1
/ 18:-d31 PC; deuterated
DOPC; deuterated PC;
d-DOPC; Dioleoyl
lecithin-d31; 18:1 (Cis)
PC-d31
Formula:C44H53D31NO8P
Formula Weight: 817.3
Deuterium enrichment: 96-99% except
60-80% on the alpha positions
Contains < 10% of the
1-d31
isomer
Purity: 99%
Supplied as: solid
Storage: -20°C under argon
Stability: ≥ 2 years
DOPC-d62
1,2-dioleoyl-d62-sn-glycero-3-phosphocholine
Catalog #1504
CAS # 4235-95-4 (unlabeled)
Synonyms: d62-DOPC;
1,2-dioctadecenoyl-d62-sn-glycero-3-phosphocholine;
Dioleoyl
phosphatidylcholine-d62;
18:1-d31 /
18:1-d31 PC;
deuterated DOPC; deuterated PC
Formula:C44H22D62NO8P
Formula Weight: 848.5
Deuterium enrichment: 96-99% except
60-80% on the alpha positions
Purity: 99%
Supplied as: solid
Storage: -20°C under argon
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, ESI-MS, TLC)
Citations of this product:
Motlaq, V. F., Adlmann, F. A., Hernández, V. A., Vorobiev, A., Wolff, M., & Bergström, L. M. (2022). Dissolution mechanism of supported phospholipid bilayer in the presence of amphiphilic drug investigated
DLinPC-d9
1,2-Dilinoleoyl-sn-glycero-3-phosphocholine-d9
Catalog #0545
CAS # 998-06-1(unlabeled)
Synonyms: d9-DLinPC;
1,2-Dioctadecadienoyl-sn-glycero-3-phosphocholine-d9;
Dilinoleoyl
phosphatidylcholine-d9; 18:2
PC-d9;
deuterated DLinPC; deuterated PC;
d-DLPC; 18:2 (Cis) PC-d9
Formula:C44H71D9NO8P
Formula Weight: 791.1
Deuterium enrichment: 99%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
PSPC-d66
1-Palmitoyl-d31-2-stearoyl-d35-sn-glycero-3-phosphocholine
Catalog #1519
CAS # 59403-51-9 (unlabeled)
Synonyms: d66-PSPC;
1-hexadecanoyl-d31-2-octadecanoyl-d35-sn-glycero-3-phosphocholine;
Palmitoyl stearoyl
phosphatidylcholine-d66;
16:0-d31 /
18:0-d35 PC;
deuterated PSPC; deuterated PC; d-PSPC;
18:0 16:0 - d66
Formula:C42H18D66NO8P
Formula Weight: 828.5
Deuterium enrichment: ≥ 97% D on all
fatty acid positions except 50-70% D on
alpha
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
ESI-MS (+) ; TLC (CHCl3:MeOH:NH4OH)
Citations of this product:
Motlaq, V. F., Adlmann, F. A., Hernández, V. A., Vorobiev, A., Wolff, M., & Bergström, L. M. (2022). Dissolution mechanism of supported phospholipid bilayer in the presence of amphiphilic drug investigated
Also available on request:
- Phosphatidylcholines containing any other combination of fatty acids, including rare fatty acids, oxidized fatty acids, free radical labeled fatty acids, and 13C-labeled fatty acids.
- Fatty acid deuteration over 99%
- 13C- and 15N-labeling of the head group
- Perdeuteration of the lipid
DMPG-d54
1,2-Dimirystoyl-d54-sn-glycero-3-phospho-rac-(1-glycerol) (ammonium salt)
Catalog #0502
CAS # 200880-40-6 (unlabeled)
CAS # 326495-45-8 (labeled)
Synonyms: d54-DMPG;
1,2-Ditetradecanoyl-d54-sn-glycero-3-phospho-rac-(1-glycerol);
Dimyristoyl phosphatidylglycerol-d54;
14:0-d27 / 14:0-d27 PG;
deuterated DMPG; deuterated PG; d-DMPG; 14:0
PG-d54
Formula:C34H12D54NO10P
Formula Weight: 738.2
Deuterium enrichment: 98% except 60-80% on the
alpha positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, TLC, ESI-MS)
Citations of our product:
Hagn, F., Etzkorn, M., Raschle, T., & Wagner, G. (2013). Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins. Journal of the American Chemical Society, 135(5), 1919-1925.Hagn, F., & Wagner, G. (2015). Structure refinement and membrane positioning of selectively labeled OmpX in phospholipid nanodiscs. Journal of biomolecular NMR, 61, 249-260.
Hagn, F., Nasr, M. L., & Wagner, G. (2018). Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR. Nature protocols, 13(1), 79-98.
Schuster, M., Deluigi, M., Pantić, M., Vacca, S., Baumann, C., Scott, D. J., ... & Zerbe, O. (2020). Optimizing the α1B-adrenergic receptor for solution NMR studies. Biochimica et Biophysica Acta (BBA)-Biomembranes, 1862(10), 183354.
Gaussmann, S., Gopalswamy, M., Eberhardt, M., Reuter, M., Zou, P., Schliebs, W., ... & Sattler, M. (2021). Membrane interactions of the peroxisomal proteins PEX5 and PEX14. Frontiers in Cell and Developmental Biology, 9, 651449.
Daniilidis, M., Brandl, M. J., & Hagn, F. (2022). The advanced properties of circularized MSP nanodiscs facilitate high-resolution NMR studies of membrane proteins. Journal of Molecular Biology, 434(24), 167861.
DPPG-d62
1,2-Dipalmitoyl-d62-sn-glycero-3-phospho-rac-(1-glycerol) (ammonium salt)
Catalog #2517
CAS # 200880-41-7 (unlabeled)
CAS # 326495-46-9 (labeled)
Synonyms: d62-DPPG;
1,2-Dihexadecanoyl-d62-sn-glycero-3-phospho-rac-(1-glycerol);
Dipalmitoyl phosphatidylglycerol-d62;
16:0-d31 / 16:0-d31 PG;
Deuterated DPPG; Deuterated PG; Deuterated
phosphatidylglycerol; d-DPPG; 16:0 PG -
d62
Formula:C38H18D62NO10P
Formula Weight: 802.4
Deuterium enrichment: ≥ 97% except 60-80% on the
alpha positions
* > 99 % D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DSPG-d70
1,2-distearoyl-d70-sn-glycero-3-phospho-rac-(1-glycerol) (ammonium salt)
Catalog #2518
CAS # 200880-42-8 (unlabeled)
CAS # 326495-47-0 (labeled)
Synonyms: d70-DSPG;
1,2-Dioctadecanoyl-d70-sn-glycero-3-phospho-rac-(1-glycerol);
Distearoyl phosphatidylglycerol-d70;
18:0-d35 / 18:0-d35 PG;
18:0 PG - d70;
Deuterated DSPG; Deuterated PG; d-DSPG;
Deuterated phosphatidylglycerol;
d-phosphatidylglycerol
Formula:C42H16D70NO10P
Formula Weight: 866.5
Deuterium enrichment: ≥ 97% except 60-80% on the
alpha positions
* > 99 % D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
POPG-d62
1-Palmitoyl-d31-2-oleoyl-d31-sn-glycero-3-phospho-rac-(1-glycerol) (ammonium salt)
Catalog #1502
CAS # 268550-95-4 (unlabeled)
Synonyms: d62-DPPG;
1-Hexadecanoyl-d31-2-octadecenoyl-d31-sn-glycero-3-phospho-rac-(1-glycerol);
Palmitoyl oleoyl
phosphatidylglycerol-d62;
16:0-d31 / 18:1-d31 PG;
deuterated POPG; deuterated PG
Formula:C40H18D62NO10P
Molecular Weight: 828.4
Deuterium enrichment: 96-99% except 60-80% on
the
alpha positions and natural abundance at the
vinyl
positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DOPG-d62
1,2-Dioleoyl-d62-sn-glycero-3-phospho-rac-(1-glycerol) (ammonium salt)
Catalog #1505
CAS # 67254-28-8 (unlabeled)
Synonyms: d62-DOPG;
1,2-Dioctadecenoyl-d62-sn-glycero-3-phospho-rac-(1-glycerol);
Dioleoyl phosphatidylglycerol-d62;
18:1-d31 / 18:1-d31 PG;
18:1
PG - d62; deuterated DOPG; deuterated
PG;
d-DOPG; 18:1 (Cys) PG - d62
Formula:C42H20D62NO10P
Molecular Weight: 854.5
Deuterium enrichment: 96-99% except 60-80% on
the
alpha positions; Natural abundance of the vinyl
positions.
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Also available on request:
- Phosphatidylglycerols containing any other combination of fatty acids, including rare fatty acids, oxidized fatty acids, free radical labeled fatty acids, and 13C-labeled fatty acids.
- Fatty acid deuteration over 99%
- Deuteration and 13C-labeling of the head group
- Perdeuteration of the lipid
DH6PE-d22
1,2-Dihexanoyl-d22-sn-glycero-3-phosphoethanolamine
Catalog #1103
CAS # 96893-06-0 (unlabeled)
Synonyms: DC6PE-d22;
D6PE-d22; DH6PE-d22;
DHPE-d22; d-D6PE; Deuterated DC6PE;
1,2-Dicaproyl-d22-sn-glycero-3-phosphoethanolamine;
Dicaproyl phosphatidylethanolamine; 6:0
PE-d22
Formula:C17H12D22NO8P
Formula Weight: 433.6
Deuterium enrichment: ≥98%D on all fatty acid
positions except 50-70% D on alpha
;99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DH7PE-d26
1,2-Diheptanoyl-d26-sn-glycero-3-phosphoethanolamine
Catalog #1104
Synonyms: D7PC-d26;
DC7PC-d26; DH7PC-d26;
DHPC-d26; Deuterated DC7PE;
Deuterated DH7PE;
1,2-dienanthioyl-d26-sn-glycero-3-phosphoethanolamine;
Dienanthioyl phosphatidylethanolamine;
Deuterated PE; 7:0-d13 / 7:0-d13 PE;
7:0 PE-d26
Formula:C19H12D26NO8P
Formula Weight: 465.6
Deuterium enrichment: ≥98%D on all fatty acid
positions except 50-70% D on alpha
;99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DLPE-d46
1,2-Dilauroyl-d46-sn-glycero-3-phosphoethanolamine
Catalog #1500
CAS #59752-57-7 (unlabeled)
Synonyms: D-DLPE; Deuterated PE; Deuterated
DLPE;
DLPE-d46;
1,2-Didodecanoyl-d46-sn-glycero-3-phosphoethanolamine;
12:0-d23 / 12:0-d23 PE;
Dilauroyl
phosphatidylethanolamine-d46; 12:0 PE
-
d46
Formula:C29H12D46NO8P
Formula Weight: 626.0
Deuterium enrichment: ≥98% on all fatty acid
positions
except 50-70% D on alpha
;99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DMPE-d54
1,2-Dimyristoyl-d54-sn-glycero-3-phosphoethanolamine
Catalog #0555
CAS # 998-07-2 (unlabeled)
CAS # 326495-41-4 (labeled)
Synonyms: d54-DMPE;
1,2-ditetradecanoyl-d54-sn-glycero-3-phosphoethanolamine;
Dimyristoyl
phosphatidylethanolamine-d54;
14:0-d27 / 14:0-d27 PE;
deuterated DMPE; deuterated PE; d-DMPE; 14:0 PE
-
d54
Formula:C33H12D54NO8P
Formula Weight: 690.2
Deuterium enrichment: >98% except 60-80% on the
alpha
positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
1H-NMR ; 31P-NMR (1:1 CD3OD:CDCl3)
DPPE-d62
1,2-Dipalmitoyl-d62-sn-glycero-3-phosphoethanolamine
Catalog #1611
CAS # 923-61-5 (unlabeled)
CAS # 326495-42-5 (labeled)
Synonyms: d62-DPPE;
1,2-dihexadecanoyl-d62-sn-glycero-3-phosphoethanolamine;
Dipalmitoyl
phosphatidylethanolamine-d62;
16:0-d31 / 16:0-d31 PE;
deuterated
DPPE;
deuterated PE; d-DPPE; 16:0
PE-d62
Formula:C37H12D62NO8P
Formula Weight: 754.3
Deuterium enrichment: 97% except 60-80% on the
alpha
positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data
1H-NMR, 31P-NMR, TLC
DSPE-d70
1,2-Distearoyl-d70-sn-glycero-3-phosphoethanolamine
Catalog #1102
CAS # 1069-79-0 (unlabeled)
CAS # 326495-43-6 (labeled)
Synonyms: d70-DSPE;
1,2-Dioctadecanoyl-d70-sn-glycero-3-phosphoethanolamine;
18:0-d35 / 18:0-d35 PE;
deuterated
DSPE; deuterated PE; d-DSPE; 18:0
PE-d70
Formula:C41H12D70NO8P
Formula Weight: 818.5
Deuterium enrichment: 98% except 60-80% on the
alpha
positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
POPE-d62
1-Palmitoyl-d31-2-oleoyl-d31-sn-glycero-3-phosphoethanolamine
Catalog #1101
CAS # 26662-94-2 (unlabeled)
Synonyms: d62-POPE;
1-hexadecanoyl-d31-2-octadecenoyl-d31-sn-glycero-3-phosphoethanolamine;
Palmitoyl oleoyl
phosphatidylethanolamine-d62;
16:0-d31 / 18:1-d31 PE;
Deuterated POPE; deuterated PE; d-POPE
Formula:C39H14D62NO8P
Formula Weight: 780.4
Deuterium enrichment: 98% except 60-80% on the
alpha
positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DOPE-d62
1,2-Dioleoyl-d62-sn-glycero-3-phosphoethanolamine
Catalog #0519
CAS # 4004-05-1 (unlabeled)
Synonyms: d62-DOPE;
1,2-Dioctadecenoyl-d62-sn-glycero-3-phosphoethanolamine;
Dioleoyl
phosphatidylethanolamine-d62;
18:1-d31 / 18:1-d31 PE;
deuterated DOPE;
deuterated PE; d-DOPE; 18:1 (9Z) PE -
d62
Formula:
C41H16D62NO8P
Formula Weight: 806.4
Deuterium enrichment: 96-99% except 60-80% on
the alpha positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
ESI-MS (+)
TLC
Also available on request:
- Phosphatidylethanolamines containing any other combination of fatty acids, including rare fatty acids, oxidized fatty acids, free radical labeled fatty acids, and 13C-labeled fatty acids.
- Fatty acid deuteration over 99%
- Deuteration, 13C- and 15N-labeling of the head group
- Perdeuteration of the lipid
DMPS-d3
1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine-d3 (ammonium salt)
Catalog #05181
CAS # 105405-50-3 (unlabeled)
Synonyms: d3-DMPS;
1,2-ditetradecanoyl-sn-glycero-phospho-L-serine-d3;
Dimyristoyl phosphatidylserine-d3;
14:0 / 14:0 PS-d3; 14:0 PS -
d3;
Deuterated DMPS; Deuterated PS; Deuterated
phosphatidylserine;
d3-phosphatidylserine;
d-phosphatidylserine
Formula:
C34H66D3N2O10P
Formula Weight: 699.9
Deuterium enrichment: 98%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DMPS-d54
1,2-Dimyristoyl-d54-sn-glycero-3-phospho-L-serine (ammonium salt)
Catalog #0518
CAS # 105405-50-3 (unlabeled)
CAS # 327178-93-8 (labeled)
Synonyms: d54-DMPS;
1,2-ditetradecanoyl-d54-sn-glycero-3-phospho-L-serine;
Dimyristoyl phosphatidylserine-d54;
14:0-d27 / 14:0-d27 PS;
deuterated DMPS; Deuterated PS;
Deuterated phosphatidylserine;
d54-phosphatidylserine;
d-phosphatidylserine
Formula:
C34H15D54N2O10P
Formula Weight: 751.2
Deuterium enrichment: ≥98% on all fatty acid
positions except 50-70%D on alpha carbons
*≥99%D available on request
Purity: 98%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DPPS-d3
1,2-Dipalmitoyl-sn-glycero-3-phospho-L-serine-d3 (ammonium salt)
Catalog #16081
CAS # 145849-32-7 (unlabeled)
Synonyms: d3-DPPS;
1,2-Dihexadecanoyl-sn-glycero-3-phospho-L-serine-d3;
Dipalmitoyl phosphatidylserine-d3;
16:0 / 16:0 PS-d3; 16:0
PS-d3; deuterated PS; Deuterated
DPPS; Deuterated PS;
Deuterated phosphatidylserine;
d3-phosphatidylserine;
d-phosphatidylserine
Formula:
C38H74D3N2O10P
Formula Weight: 756
Deuterium enrichment: 98%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DPPS-d62
1,2-Dipalmitoyl-d62-sn-glycero-3-phospho-L-serine (ammonium salt)
Catalog #1608
CAS # 145849-32-7 (unlabeled)
CAS # 327178-94-9 (labeled)
Synonyms: d62-DPPS;
1,2-Dihexadecanoyl-d62-sn-glycero-3-phospho-L-serine;
Dipalmitoyl phosphatidylserine-d62;
16:0-d31 / 16:0-d31 PS;
deuterated DPPS; deuterated PS;
Deuterated phosphatidylserine;
d62-phosphatidylserine;
d-phosphatidylserine; 16:0 PS- d62
Formula:
C38H16D62N2O10P
Formula Weight: 815.4
Deuterium enrichment: ≥98% on all fatty acid
positions except 50-70%D on alpha carbons
*≥99%D available on request
Purity: 98%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data
PSPS-d66
1-Palmitoyl-d31-2-stearoyl-d35-sn-glycero-3-phospho-L-serine (ammonium salt)
Catalog #1606
Synonyms: d66-PSPS; 1-Hexadecanoyl-d31-octadecanoyl-d35-sn-glycero-3-phospho-L-serine; 16:0-d31 / 18:0-d35 PS; deuterated PSPS; deuterated PS; d-PSPS; 18:0 PS-d70; d70-phosphatidylserine; d-phosphatidylserine; Deuterated phosphatidylserine
Formula: C40H15D66N2O10P
Formula Weight: 847.5
Deuterium enrichment: ≥98% on all fatty acid positions except 50-70%D on alpha carbons ;≥99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data
DSPS-d3
1,2-Distearoyl-sn-glycero-3-phospho-L-serine-d3 (ammonium salt)
Catalog #1811
CAS # 321595-13-5 (unlabeled)
Synonyms: d3-DSPS;
1,2-Dioctadecanoyl-d62-sn-glycero-3-phospho-L-serine;
Distearoyl phosphatidylserine-d3;
18:0 PS-d3; deuterated DSPS;
deuterated PS; d-DPPS;
d3-phosphatidylserine;
d-phosphatidylserine; Deuterated
phosphatidylserine
Formula:
C42H82D3N2O10P
Formula Weight: 812.1
Deuterium enrichment: 98%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DSPS-d70
1,2-Distearoyl-d70-sn-glycero-3-phospho-L-serine (ammonium salt)
Catalog #1810
CAS # 321595-13-5 (unlabeled)
CAS # 327178-95-0 (labeled)
Synonyms: d70-DSPS;
1,2-Dioctadecanoyl-d62-sn-glycero-3-phospho-L-serine;
Distearoyl phosphatidylserine-d70;
18:0-d35 / 18:0-d35 PS;
deuterated DSPS; deuterated PS; d-DSPS; 18:0
PS-d70;
d70-phosphatidylserine;
d-phosphatidylserine; Deuterated
phosphatidylserine
Formula:
C42H17D70N2O10P
Formula Weight: 879.5
Deuterium enrichment: ≥98% on all fatty acid
positions except 50-70%D on alpha carbons
;≥99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
POPS-d3
1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine-d3 (ammonium salt)
Catalog #16022
CAS # 321863-21-2 (unlabeled)
Synonyms: d3-POPS; d-POPS;
1-hexadecanoyl-2-octadecenoyl-sn-glycero-3-phospho-L-serine-d3;
Palmitoyl oleoyl
phosphatidylserine-d3; 16:0 / 18:1
PS-d3; deuterated POPS; deuterated
PS
Formula:
C40H76D3N2O10P
Formula Weight: 782.1
Deuterium enrichment:
96-99% except 60-80% on the alpha positions
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
POPS-d62
1-Palmitoyl-d31-2-oleoyl-d31-sn-glycero-3-phospho-L-serine (ammonium salt)
Catalog #16021
CAS # 321863-21-2 (unlabeled)
Synonyms: d62-POPS; d-POPS;
1-hexadecanoyl-d31-2-octadecenoyl-d31-sn-glycero-3-phospho-L-serine;
Palmitoyl oleoyl
phosphatidylserine-d62;
16:0-d31 / 18:1-d31 PS;
deuterated POPS; deuterated PS
Formula:
C40H17D62N2O10P
Formula Weight: 841.4
Deuterium enrichment: 96-99% except 60-80% on
the alpha positions
Purity: 98%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DOPS-d3
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d3 (ammonium salt)
Catalog #15062
CAS # 90693-88-2 (unlabeled)
Synonyms: d3-DOPS;
1,2-dioctadecenoyl-sn-glycero-3-phospho-L-serine-d3;
Deuterated DOPS; 18:1 PS-d3; 18:1
(Cis) - d3;
Deuterated phosphatidylserine; d-DOPS; Dioleoyl
phosphatidylserine-d3; 18:1 / 18:1
PS-d3;
Deuterated DOPS; Deuterated PS
Formula:
C42H78D3N2O10P
Formula Weight: 808.1
Deuterium enrichment: 98%
Purity: 98%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DOPS-d62
1,2-Dioleoyl-d62-sn-glycero-3-phospho-L-serine (ammonium salt)
Catalog #15061
CAS # 90693-88-2 (unlabeled)
Synonyms: Deuterated DOPS; Deuterated PS; 18:1
PS-d62; 18:1 (Cis) -d62;
d62-DOPS;
1,2-dioctadecenoyl-d62-sn-glycero-3-phospho-L-serine;
Deuterated phosphatidylserine; d-DOPS;
Dioleoyl phosphatidylserine-d62;
18:1-d31 / 18:1-d31 PS;
Deuterated PS
Formula:
C42H19D62N2O10P
Formula Weight: 867.5
Deuterium enrichment: 96-99% except 60-80% on
the alpha positions
Purity: 98%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DLinPS-d3
1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine-d3 (ammonium salt)
Catalog #0544
CAS # 321883-39-0 (unlabeled)
Synonyms: d3-DLinPS;
1,2-Dioctadecadienoyl-sn-glycero-3-phospho-L-serine-d3;
Dioctadecadienoyl
phosphatidylserine-d3; 18:2 / 18:2
PS-d3;
Deuterated DLinPS; Deuterated PS;
18:2 (Cis) PS - d3; d-DLinPS;
deuterated DLPS; DLPS-d3
Formula:
C42H74D3N2O10P
Formula Weight: 804.1
Deuterium enrichment: 98%
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, TLC, ESI-MS)
Also available on request:
- Phosphatidylserines containing any other combination of fatty acids, including rare fatty acids, oxidized fatty acids, free radical labeled fatty acids, and 13C-labeled fatty acids.
- Fatty acid deuteration over 99%
- Deuteration, 13C- and 15N-labeling of the head group
- Perdeuteration of the lipid
LMPC-d27
1-Myristoyl-d27-2-lyso-sn-glycero-3-phosphocholine
Catalog # 1201
CAS # 326495-21-0 (unlabeled)
Synonyms: Deuterated
lyso-myristoylphosphocholine;
1-Myristoyl-d27-2-OH-sn-glycero-3-phosphocholine;
d-LMPC; deuterated LMPC; Deuterated
lyso-PC;
1-Tetradecanoyl-d27-2-lyso-sn-glycero-3-phosphocholine;
14:0-d27/ 0:0 PC; 14:0
Lyso
PC-d27
Formula:
C22H19D27NO7P
Formula Weight: 494.7
Deuterium enrichment: ≥ 98% except
60-80% on alpha positions ;99%D
available on request
Purity: 99% (both isomers)
Contains ≤ 10% of the 2'-acyl
isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
LPPC-d31
1-Palmitoyl-d31-2-lyso-sn-glycero-3-phosphocholine
Catalog # 1217
CAS # 17364-16-8 (unlabeled)
Synonyms:
1-Palmitoyl-d31-2-OH-sn-glycero-3-phosphocholine;
Deuterated
lyso-palmitoylphosphocholine;
d-LPPC; deuterated LPPC; Deuterated
lyso-PC;
1-Hexadecanoyl-d31-2-lyso-sn-glycero-3-phosphocholine;
16:0-d27/ 0:0 PC; 16:0
Lyso
PC-d31
Formula:
C24H19D31NO7P
Formula Weight: 526.6
Deuterium enrichment: ≥ 98% except
60-80% on alpha positions
;99%D available on request
Purity: 99% (both isomers)
Contains ≤ 10% of the 2'-acyl
isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: 1H-NMR, 31P-NMR
LMPG-d27
1-Myristoyl-d27-2-lyso-sn-glycero-3-phosphoglycerol
Catalog # 1203
CAS # 326495-21-0 (unlabeled)
Synonyms: Lyso myristoyl
phosphoglycerol; deuterated lyso-PG;
d-LMPG; deuterated lyso lipid;
1-tetradecanoyl-d27-2-lyso-sn-glycero-3-phosphoglycerol;
14:0-d27/ 0:0 PG;
1-myristoyl-d31-2-hydroxy-sn-glycero-3-phosphoglycerol;deuterated
1-myristoyl-2-OH-sn-glycero-3-phosphoglycerol
Formula:
C20H17D27NO9P
Formula Weight: 500.7
Deuterium enrichment: ≥ 98% except
60-80% on alpha positions; 99%D
available on request
Purity: 99%
Contains ≤ 10% of the 2'-acyl isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, ESI-MS, TLC)
Citations of our product:
Klammt, C., Maslennikov, I., Bayrhuber, M., Eichmann, C., Vajpai, N., Chiu, E. J. C., ... & Choe, S. (2012). Facile backbone structure determination of human membrane proteins by NMR spectroscopy. Nature methods, 9(8), 834-839.Brady, J. P., Claridge, J. K., Smith, P. G., & Schnell, J. R. (2015). A conserved amphipathic helix is required for membrane tubule formation by Yop1p. Proceedings of the National Academy of Sciences, 112(7), E639-E648.
Taylor, K. C., Kang, P. W., Hou, P., Yang, N. D., Kuenze, G., Smith, J. A., ... & Sanders, C. R. (2020). Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. Elife, 9, e53901.
LPPG-d31
1-palmitoyl-d31-2-lyso-sn-glycero-3-phosphoglycerol
Catalog # 1216
CAS # 326495-22-1 (unlabeled)
Synonyms: Lyso palmitoyl
phosphoglycerol; Deuterated lyso-PG;
d-LPPG; deuterated lyso lipid;
1-hexadecanoyl-d31-2-lyso-sn-glycero-3-phosphoglycerol;
16:0-d31/ 0:0 PG;
deuterated
1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoglycerol;
1-palmitoyl-d31-2-hydroxy-sn-glycero-3-phosphoglycerol
Formula:
C22H17D31NO9P
Formula Weight: 532.8
Deuterium enrichment: ≥ 97% except
60-80% on alpha positions; 99%D available on request
Purity: 99%
Contains ≤ 10% of the 2'-acyl isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
1H-NMR spectrum (500MHz, CD3OD)
31P-NMR spectrum
Citations of our product:
Brazin, K. N., Mallis, R. J., Li, C., Keskin, D. B., Arthanari, H., Gao, Y., ... & Reinherz, E. L. (2014). Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments. Journal of Biological Chemistry, 289(27), 18880-18892.Chadwick, A. C., Jensen, D. R., Hanson, P. J., Lange, P. T., Proudfoot, S. C., Peterson, F. C., ... & Sahoo, D. (2017). NMR structure of the C-terminal transmembrane domain of the HDL receptor, SR-BI, and a functionally relevant leucine zipper motif. Structure, 25(3), 446-457.
Brazin, K. N., Mallis, R. J., Boeszoermenyi, A., Feng, Y., Yoshizawa, A., Reche, P. A., ... & Reinherz, E. L. (2018). The T cell antigen receptor α transmembrane domain coordinates triggering through regulation of bilayer immersion and CD3 subunit associations. Immunity, 49(5), 829-841.
LMPE-d27
1-Myristoyl-d27-2-lyso-sn-glycero-3-phosphoethanolamine
Catalog # 4141
CAS # 123060-40-2 (unlabeled)
Synonyms:
Deuterated
lyso-myristoylphosphoethanolamine;
1-Myristoyl-d27-2-OH-sn-glycero-3-phosphoethanolamine;
d-LMPE; deuterated LMPE; Deuterated
lyso-PE;
1-Tetradecanoyl-d27-2-lyso-sn-glycero-3-phosphoethanolamine;
14:0-d27/ 0:0 PE; 14:0
Lyso PE-d27
Formula:
C19H13D27NO7P
Formula Weight: 452.7
Deuterium enrichment: ≥ 98% except
60-80% on alpha positions
;99%D available on request
Purity: 99% (both isomers)
Contains ≤ 10% of the 2'-acyl
isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
LPPE-d31
1-Palmitoyl-d31-2-lyso-sn-glycero-3-phosphoethanolamine
Catalog # 4161
CAS # 53862-35-4 (unlabeled)
Synonyms: Deuterated
lyso-palmitoylphosphoethanolamine;
16:0 Lyso PE-d31;
1-Palmitoyl-d31-2-OH-sn-glycero-3-phosphoethanolamine;
d-LPPE; deuterated LPPE; Deuterated
lyso-PE;
1-Hexadecanoyl-d31-2-lyso-sn-glycero-3-phosphoethanolamine;
16:0-d31/ 0:0 PE
Formula:
C21H13D31NO7P
Formula Weight: 484.8
Deuterium enrichment: ≥ 98% except
60-80% on alpha positions
;99%D available on request
Purity: 99% (both isomers)
Contains ≤ 10% of the 2'-acyl
isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
LSPE-d35
1-Stearoyl-d35-2-lyso-sn-glycero-3-phosphoethanolamine
Catalog # 4181
CAS # 69747-55-3 (unlabeled)
Synonyms: Deuterated
lyso-stearoylphosphoethanolamine;
18:0 Lyso PE-d35;
1-Stearoyl-d35-2-OH-sn-glycero-3-phosphoethanolamine;
d-LSPE; deuterated LSPE; Deuterated
lyso-PE;
1-Octadecanoyl-d35-2-lyso-sn-glycero-3-phosphoethanolamine;
18:0-d35/ 0:0 PE
Formula:
C23H13D35NO7P
Formula Weight: 516.8
Deuterium enrichment: ≥ 97% except
60-80% on alpha positions
;99%D available on request
Purity: 99% (both isomers)
Contains ≤ 10% of the 2'-acyl
isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
LOPE-d31
1-Oleoyl-d31-2-lyso-sn-glycero-3-phosphoethanolamine
Catalog # 4182
CAS # 89576-29-4 (unlabeled)
Synonyms: Deuterated
lyso-oleoylphosphoethanolamine; 18:1
Lyso PE-d31;
1-Oleoyl-d31-2-OH-sn-glycero-3-phosphoethanolamine;
d-LOPE; deuterated LOPE;
Deuterated lyso-PE;
1-Octadecenoyl-d31-2-lyso-sn-glycero-3-phosphoethanolamine;
18:1-d31/ 0:0 PE
Formula:
C23H15D31NO7P
Formula Weight: 510.8
Deuterium enrichment: 96-99% except
60-80% on the alpha positions
Purity: 99% (both isomers)
Contains ≤ 10% of the 2'-acyl
isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Other lyso-lipids available on request:
- Many polar heads, including choline, serine, glycerol, ethanolamine, and other alcohol-containing moieties, such as dyes and PEG.
- Any fatty acid, including deuterated fatty acids, rare fatty acids, oxidized fatty acids, free radical labeled fatty acids, and 13C-labeled fatty acids.
10-MAG-d24
1-Decanoyl-d19-rac-glycerol-d5
Catalog # 1321
CAS # 2277-23-8 (unlabeled)
Synonyms: Monocaprin-d24
Formula: C13H2D24O4
Molecular Weight: 270.49
Deuterium enrichment: 98%
Purity: ≥ 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Azelaic Acid-d14
Nonanedioic acid-d14
Catalog # 1001
CAS # 123-99-9 (unlabeled)
CAS # 119176-67-9 (labeled)
Synonyms: 1,9-Nonanedioic acid-d14; Deuterated azelaic
acid
Formula: C9H2D14O4
Formula Weight: 202.3
Deuterium enrichment: 98% D
Purity: ≥ 98%
Supplied as: solid
Storage: room temperature
Stability: ≥ 5 years
Data:
ESI-MS (-)
Propanoic acid-d5, sodium salt
Sodium propanoate - d5
Catalog #1006
CAS # 137-40-6 (unlabeled)
CAS # 202529-18-8 (labeled)
Synonyms: Sodium propionate-d5, Propionic
acid-d5,
sodium salt
Formula:C2D5COONa
Formula Weight: 101.09
Deuterium enrichment: 99%
Purity: 99%
Supplied as: solid
Storage: room temperature
Stability: 5 years
Citations of this product:
Dubey, A., Stoyanov, N., Viennet, T., Chhabra, S., Elter, S., Borggräfe, J., ... & Arthanari, H. (2021). Local deuteration enables NMR observation of methyl groups in proteins from eukaryotic and cell‐free expression systems. Angewandte Chemie International Edition, 60(25), 13783-13787.
Hexanoic Acid-d11
Caproic acid - d11
Catalog # 1007
CAS # 142-62-1 (unlabeled)
CAS # 95348-44-0 (labeled)
Synonyms: d-Hexanoic acid; Deuterated hexanoic acid; n-Hexanoic
аcid-d11; Hexylic аcid-d11;
Caproic аcid-d11
Formula: C9HD11O2
Formula Weight: 127.2
Deuterium enrichment: 99% D
Purity: 99%
Supplied as: liquid
Storage: room temperature
Stability: 5 years
Data:
ESI-MS (-)
Heptanoic Acid-d13
FA 7:0 - d13
Catalog # 1004
CAS # 111-14-8 (unlabeled)
CAS # 130348-93-5 (labeled)
Synonyms: Deuterated heptanoic acid, n-Heptanoic
acid-d13;
Enanthic acid-d13
Formula: C7HD13O2
Formula Weight: 143.3
Deuterium enrichment: 99%
Purity: 99%
Supplied as: liquid
Storage: room temperature
Stability: > 5 years
Octanoic acid-d15
n-Caprylic acid-d15
Catalog # 1012
CAS # 124-07-2 (unlabeled)
CAS # 69974-55-6 (labeled)
Synonyms: 1-Heptanecarboxylic acid-d15 ; n-Octylic
acid-d15
Formula: C8HD15O2
Formula Weight: 159.3
Deuterium enrichment: 99%
Purity: 99%
Supplied as: liquid
Storage: room temperature
Stability: 5 years
Nonanoic Acid-d17
Pelargonic acid - d17
Catalog # 1011
CAS # 112-05-0 (unlabeled)
CAS # 130348-94-6 (labeled)
Synonyms: d-nonanoic acid; deuterated nonanoic acid; n-Nonylic
acid-d17 ; n-Nonanoic acid-d17;
1-Octanecarboxylic acid-d17; Nonoic acid, n-Pelargonic
acid-d17
Formula: C9HD17O2
Formula Weight: 175.3
Deuterium enrichment: 99%
Purity: 99%
Supplied as: liquid
Storage: room temperature
Stability: 5 years
Decanoic Acid-d19
Capric acid-d19
Catalog # 1013
CAS # 334-48-5 (unlabeled)
CAS # 88170-22-3 (labeled)
Synonyms: Deuterated decanoic acid; d-decanoic acid; n-Capric
acid-d19
Formula: C10HD19O2
Formula Weight: 191.4
Deuterium enrichment: 99%
Purity: 99%
Supplied as: liquid
Storage: room temperature
Stability: 5 years
Undecanoic acid-d21
FA 11:0 - d21
Catalog # 1003
CAS # 60658-40-4 (labeled)
CAS # 112-37-8 (unlabeled)
Synonyms: Deuterated undecanoic acid; FA 11:0-d21;
Hendecanoic acid;
1-Decanecarboxylic acid-d21; Undecylic
acid-d21
Formula: C11HD21O2
Formula Weight: 207.4
Deuterium enrichment: 98%
Purity: 99%
Supplied as: solid
Storage: room temperature
Stability: > 5 years
Lauric Acid-d23
Dodecanoic acid-d23
Catalog # 1014
CAS # 143-07-7 (unlabeled)
CAS # 59154-43-7 (labeled)
Synonyms: FA 12:0 - d23; d-Lauric acid; Deuterated lauric
acid;
1-Dodecanecarboxylic acid- d23; Vulvic
acid-d23;
d-Dodecanoic acid;
n-Dodecanoic acid-d23
Formula: C12HD23O2
Formula Weight: 223.5
Deuterium enrichment: 98% D (> 99% D available on request)
Purity: 99%
Supplied as: solid
Storage: room temperature
Stability: 5 years
Tridecanoic Acid-d25
FA 13:0 - d25
Catalog # 1005
CAS # 334-48-5 (unlabeled)
CAS # 88170-22-3 (labeled)
Synonyms: Deuterated tridecanoic acid; n-Tridecoic
acid-d25;
n-Tridecanoic acid-d25;
Tridecylic acid-d25
Formula: C13HD25O2
Formula Weight: 239.5
Deuterium enrichment: 98%
Purity: 99%
Supplied as: solid
Storage: room temperature
Stability: 5 years
Myristic Acid-d27
Tetradecanoic acid-d27
Catalog # 1015
CAS # 544-63-8 (unlabeled)
CAS # 60658-41-5 (labeled)
Synonyms: FA 14:0 - d27; d-Myristic acid; Deuterated
myristic
acid; 1-Tridecanecarboxylic acid- d27;
n-Tetradecanoic acid-d27
Formula: C14HD27O2
Formula Weight: 255.5
Deuterium enrichment: 98 % (>99% D available on request)
Purity: 99%
Supplied as: solid
Storage: room temperature
Stability: 5 years
Palmitic Acid-d31
Hexadecanoic acid-d31
Catalog # 1016
CAS # 57-10-3 (unlabeled)
CAS # 39756-30-4 (labeled)
Synonyms: FA 16:0 -d31;n-Hexadecanoic
acid-d31;
1-Pentadecanecarboxylic acid-d31;,
Cetostearic acid-d31; d-Palmitic acid; Deuterated
palmitic
acid
Formula: C16HD31O2
Formula Weight: 287.6
Deuterium enrichment: 98% (>99% D available on request)
Purity: 99%
Supplied as: solid
Storage: room temperature
Stability: 5 years
Stearic Acid-d35
n-Octadecanoic acid-d35
Catalog #1017
CAS # 57-11-4 (unlabeled)
CAS # 17660-51-4 (labeled)
Synonyms: FA 18:0 - d35; n-Octadecanoic
acid-d35;
1-Heptadecanecarboxylic acid-d35
Formula: C18HD35O2
Formula Weight: 319.7
Deuterium enrichment: 98%
*>99% available on request
Purity: 99%
Supplied as: solid
Storage: room temperature
Stability: 5 years
Data:
ESI-MS (-)
Phytanic Acid-d39
3,7,11,15-Tetramethylhexadecanoic acid-d39
Catalog #1002
CAS # 14721-66-5 (unlabeled)
Synonyms: Deuterated phytanic acid; Deuterated
tetramethylhexadecanoic
acid
Formula:C20HD39O2
Molecular Weight: 351.8
Deuterium enrichment: 98%
Purity: 96% (mixture of isomers)
Supplied as: solid
Storage: room temperature
Stability: > 5 years
ESI-MS (-)
Citations of this product:
Bumbak, F., Movellan, K. T., Wegstroth, M., Overkamp, K., Leonov, A., Becker, S., & Andreas, L. B. (2020). Imidazole–imidazole hydrogen bonding in the pH-sensing histidine side chains of influenza A M2. Journal of the American Chemical Society, 142(6), 2704-2708.
Andreas, L. B., Reese, M., Eddy, M. T., Gelev, V., Ni, Q. Z., Miller, E. A., ... & Griffin, R. G. (2015). Structure and mechanism of the influenza A M218–60 dimer of dimers. Journal of the American Chemical Society, 137(47), 14877-14886.
Oleic Acid-d31
9(Z)-Octadecenoic acid-d31
Catalog #1008
CAS # 112-80-1 (unlabeled)
Synonyms: d-Oleic acid; 9-cis-Octadecenoic acid-d31,
Δ9-cis-Oleic acid-d31, Lubolic acid-d31, FA
18:1 -
d31;
Deuterated oleic acid; Octadec-9-enoic acid-d31
Formula: C18H3D31O2
Formula Weight: 313.7
Deuterium enrichment: 98%
Purity: 99%
Supplied as: solid
Storage: -20°C under argon
Stability: ≥ 2 years
Data:
ESI-MS (-)
Oleic acid-d14
9(Z)-Octadecenoic acid-d14
Catalog #1010
CAS # 112-80-1 (unlabeled)
Synonyms: d-Oleic acid; 9-cis-Octadecenoic acid-d14,
Δ9-cis-Oleic acid-d14,
Lubolic acid-d14, FA 18:1 - d14; Deuterated
oleic
acid; Octadec-9-enoic acid-d14
Formula: C18H20D14O2
Formula Weight: 296.7
Deuterium enrichment: 98%
Purity: 99%
Supplied as: solid
Storage: -20°C under argon
Stability: ≥ 2 years
Oleic acid-d17
9(Z)-Octadecenoic acid-d17
Catalog #1009
CAS # 112-80-1 (unlabeled)
CAS # 223487-44-3 (labeled)
Synonyms: d-Oleic acid; 9-cis-Octadecenoic acid-d17,
Δ9-cis-Oleic acid-d17,
Lubolic acid-d17, FA 18:1 - d17; Deuterated
oleic
acid; Octadec-9-enoic acid-d17
Formula: C18H17D17O2
Formula Weight: 299.7
Deuterium enrichment: 98%
Purity: 99%
Supplied as: solid
Storage: -20°C under argon
Stability: ≥ 2 years
We can deuterate any fatty acid to > 99% D.
Site-selective deuteration is also available.
Please inquire!
OG-d17
n-Octyl-β-D-glucopyranoside-d17
Catalog #1503
CAS # 29836-26-8 (unlabeled)
CAS # 129522-81-2 (labeled)
Synonyms: Deuterated OG; Octyl glucoside-d17
Formula:
C14H11D17O6
Molecular Weight: 309.5
Deuterium enrichment: ≥ 98%
Purity: ≥ 98 % (both anomers)
β-anomer ≥ 85 %
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
DM-d21
n-Decyl-d21-β-D-maltopyranoside
Catalog #0514
CAS # 82494-09-5 (unlabeled)
Synonyms: d21-Decyl Maltoside; Deuterated DM
Formula:
C22D21H21O11
Molecular Weight: 503.7
Deuterium enrichment: ≥ 98%
Purity: ≥ 98 % (both anomers)
β-anomer ≥ 85 % (HPLC, NMR)
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
1H-NMR
13C-NMR
DDM-d25
n-Dodecyl-d25-β-D-maltopyranoside
Catalog #0513
CAS # 849110-74-3
Synonyms: d25-Lauryl Maltoside; Deuterated
DDM
Formula:
C24H21D25O11
Molecular Weight: 535.8
Deuterium enrichment: ≥ 98%
Purity: ≥ 98 % (both anomers)
β-anomer ≥ 85 % (HPLC, NMR)
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (TLC, HPLC, ESI-MS, 1H-NMR, 13C-NMR)
Citations of our product:
Bumbak, F., Pons, M., Inoue, A., Paniagua, J.C., Yan, F., Wu, H., Robson, S.A., Bathgate, R.A., Scott, D.J., Gooley, P.R. and Ziarek, J.J., 2023. Ligands selectively tune the local and global motions of neurotensin receptor 1 (NTS1). Cell reports, 42(1).Bumbak, F., Pons, M., Inoue, A., Paniagua, J.C., Yan, F., Wu, H., Robson, S.A., Bathgate, R.A., Scott, D.J., Gooley, P.R. and Ziarek, J.J., 2023. Ligands selectively tune the local and global motions of neurotensin receptor 1 (NTS1). Cell reports, 42(1).
DDMb-d25
n-Dodecyl-d25-β-D-melibioside
Catalog #0553
CAS # 129932-38-3 (unlabeled)
Synonyms:
d25-Lauryl Melibioside; d-DDMb; deuterated
DDMb; d-Dodecyl melibioside; Deuterated dodecyl
melibioside;
d25-dodecyl
6-O-α-D-Galactopyranosyl-D-Glucopyranoside; Deuterated
ME-12;
Formula:
C24H21D25O11
Formula Weight: 535.8
Deuterium enrichment: ≥ 97% * > 99 % D available on
request
Purity: ≥ 99 %
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data:(TLC, ESI-MS, 1H-NMR, 13C-NMR)
LMNG-d42
Lauryl maltose neopentyl glycol-d42
Catalog #1204
CAS # (unlabeled) 1257852-96-2
Synonyms:
2,2-didecylpropane-1,3-bis-β-D-maltopyranoside-d42;
Deuterated neopentyl glycol; deuterated LMNG;
d-NG310
Formula:
C49H50D42O20
Formula Weight: 1043.5
Deuterium enrichment: 99%
Purity: 99% (including anomers)
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: 1H-NMR spectrum (500 MHz, CD3OD)
Citations of our product:
Baumann, C., Chiang, W. C., Valsecchi, R., Jurt, S., Deluigi, M., Schuster, M., ... & Zerbe, O. (2023). Side‐chain dynamics of the α1B‐adrenergic receptor determined by NMR via methyl relaxation. Protein Science, 32(11), e4801.
LMPG-d27
1-Myristoyl-d27-2-lyso-sn-glycero-3-phosphoglycerol
Catalog # 1203
CAS # 326495-21-0 (unlabeled)
Synonyms: Lyso myristoyl
phosphoglycerol; deuterated lyso-PG;
d-LMPG; deuterated lyso lipid;
1-tetradecanoyl-d27-2-lyso-sn-glycero-3-phosphoglycerol;
14:0-d27/ 0:0 PG;
1-myristoyl-d31-2-hydroxy-sn-glycero-3-phosphoglycerol;deuterated
1-myristoyl-2-OH-sn-glycero-3-phosphoglycerol
Formula:
C20H17D27NO9P
Formula Weight: 500.7
Deuterium enrichment: ≥ 98% except
60-80% on alpha positions; 99%D
available on request
Purity: 99%
Contains ≤ 10% of the 2'-acyl isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, ESI-MS, TLC)
Citations of our product:
Klammt, C., Maslennikov, I., Bayrhuber, M., Eichmann, C., Vajpai, N., Chiu, E. J. C., ... & Choe, S. (2012). Facile backbone structure determination of human membrane proteins by NMR spectroscopy. Nature methods, 9(8), 834-839.Brady, J. P., Claridge, J. K., Smith, P. G., & Schnell, J. R. (2015). A conserved amphipathic helix is required for membrane tubule formation by Yop1p. Proceedings of the National Academy of Sciences, 112(7), E639-E648.
Taylor, K. C., Kang, P. W., Hou, P., Yang, N. D., Kuenze, G., Smith, J. A., ... & Sanders, C. R. (2020). Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. Elife, 9, e53901.
LPPG-d31
1-palmitoyl-d31-2-lyso-sn-glycero-3-phosphoglycerol
Catalog # 1216
CAS # 326495-22-1 (unlabeled)
Synonyms: Lyso palmitoyl
phosphoglycerol; Deuterated lyso-PG;
d-LPPG; deuterated lyso lipid;
1-hexadecanoyl-d31-2-lyso-sn-glycero-3-phosphoglycerol;
16:0-d31/ 0:0 PG;
deuterated
1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoglycerol;
1-palmitoyl-d31-2-hydroxy-sn-glycero-3-phosphoglycerol
Formula:
C22H17D31NO9P
Formula Weight: 532.8
Deuterium enrichment: ≥ 97% except
60-80% on alpha positions; 99%D available on request
Purity: 99%
Contains ≤ 10% of the 2'-acyl isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
1H-NMR spectrum (500MHz, CD3OD)
31P-NMR spectrum
Citations of our product:
Brazin, K. N., Mallis, R. J., Li, C., Keskin, D. B., Arthanari, H., Gao, Y., ... & Reinherz, E. L. (2014). Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments. Journal of Biological Chemistry, 289(27), 18880-18892.Chadwick, A. C., Jensen, D. R., Hanson, P. J., Lange, P. T., Proudfoot, S. C., Peterson, F. C., ... & Sahoo, D. (2017). NMR structure of the C-terminal transmembrane domain of the HDL receptor, SR-BI, and a functionally relevant leucine zipper motif. Structure, 25(3), 446-457.
Brazin, K. N., Mallis, R. J., Boeszoermenyi, A., Feng, Y., Yoshizawa, A., Reche, P. A., ... & Reinherz, E. L. (2018). The T cell antigen receptor α transmembrane domain coordinates triggering through regulation of bilayer immersion and CD3 subunit associations. Immunity, 49(5), 829-841.
LMPC-d27
1-Myristoyl-d27-2-lyso-sn-glycero-3-phosphocholine
Catalog # 1201
CAS # 326495-21-0 (unlabeled)
Synonyms: Deuterated
lyso-myristoylphosphocholine;
1-Myristoyl-d27-2-OH-sn-glycero-3-phosphocholine;
d-LMPC; deuterated LMPC; Deuterated lyso-PC;
1-Tetradecanoyl-d27-2-lyso-sn-glycero-3-phosphocholine;
14:0-d27/ 0:0 PC; 14:0 Lyso
PC-d27
Formula:
C22H19D27NO7P
Formula Weight: 494.7
Deuterium enrichment: ≥ 98% except 60-80% on
alpha
positions ;99%D available on request
Purity: 99% (both isomers)
Contains ≤ 10% of the 2'-acyl isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
LPPC-d31
1-Palmitoyl-d31-2-lyso-sn-glycero-3-phosphocholine
Catalog # 1217
CAS # 17364-16-8 (unlabeled)
Synonyms:
1-Palmitoyl-d31-2-OH-sn-glycero-3-phosphocholine;
Deuterated lyso-palmitoylphosphocholine;
d-LPPC; deuterated LPPC; Deuterated lyso-PC;
1-Hexadecanoyl-d31-2-lyso-sn-glycero-3-phosphocholine;
16:0-d27/ 0:0 PC; 16:0 Lyso
PC-d31
Formula:
C24H19D31NO7P
Formula Weight: 526.6
Deuterium enrichment: ≥ 98% except 60-80% on
alpha positions
;99%D available on request
Purity: 99% (both isomers)
Contains ≤ 10% of the 2'-acyl isomer
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: 1H-NMR, 31P-NMR
DH6PC-d22
1,2-Dihexanoyl-d22-sn-glycero-3-phosphocholine
Catalog #0601
CAS # 34506-67-7 (unlabeled)
CAS # 328946-18-5 (labeled)
Synonyms: d22-DH6PC;
d22-D6PC;
d-DC6PC; d-DH6PC; d-D6PC;
d-DC6PC
1,2-Dicaproyl-d22-sn-glycero-3-phosphocholine;
Dicaproyl
phosphatidylcholine-d22;
6:0-d11 / 6:0-d11
PC;
6:0
PC-d22; deuterated DH6PC;
deuterated
D6PC;
deuterated DC6PC; deuterated PC;
deuterated
DHPC;
L-1,2-Dihexanoyllecithin-d22;
d22-DHPC; d-DHPC
Formula:C20H18D22NO8P
Formula Weight: 475.6
Deuterium enrichment: ≥ 98% except
60-80% on
alpha
positions
;99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (1H-NMR, 31P-NMR, ESI-MS, TLC)
Citations of this product:
Piai, A., Fu, Q., Cai, Y., Ghantous, F., Xiao, T., Shaik, M. M., ... & Chou, J. J. (2020). Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein. Nature communications, 11(1), 2317.
Bugge, K., Papaleo, E., Haxholm, G. W., Hopper, J. T., Robinson, C. V., Olsen, J. G., ... & Kragelund, B. B. (2016). A combined computational and structural model of the full-length human prolactin receptor. Nature communications, 7(1), 11578.
DH6PC-d31
1,2-Dihexanoyl-d22-sn-glycero-3-phosphocholine-d9
Catalog #0623
CAS # 34506-67-7 (unlabeled)
Synonyms: d31-DH6PC;
d31-D6PC;
d-DC6PC; d-DH6PC; d-D6PC;
1,2-Dicaproyl-d22-sn-glycero-3-phosphocholine-d9;
Dicaproyl
phosphatidylcholine-d31;
6:0-d11 / 6:0-d11
PC-d9; 6:0 PC-d31;
deuterated DH6PC; deuterated D6PC;
deuterated DC6PC;
deuterated PC;
deuterated DHPC;
L-1,2-Dihexanoyllecithin-d31;
d31-DHPC; d-DHPC
Formula:C20H9D31NO8P
Formula Weight: 484.7
Deuterium enrichment: ≥ 98% except
60-80% on
alpha
positions
;99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Citations of this product:
Bugge, K., Papaleo, E., Haxholm, G. W., Hopper, J. T., Robinson, C. V., Olsen, J. G., ... & Kragelund, B. B. (2016). A combined computational and structural model of the full-length human prolactin receptor. Nature communications, 7(1), 11578.
DH7PC-d26
1,2-Diheptanoyl-d26-sn-glycero-3-phosphocholine
Catalog # 0701
CAS # 39036-04-9 (unlabeled)
Synonyms:
d26-Diheptanoyllecithin;
1,2-dienanthioyl-d26-sn-glycero-3-phosphocholine;
Dienanthioyl
phosphatidylcholine-d26;
7:0-d13 /
7:0-d13 PC; 7:0
PC-d26;
Deuterated DH7PC; d-DH7PC;
d26-DH7PC;
Deuterated PC; Deuterated D7PC;
d26-D7PC; d-D7PC;
Deuterated
DC7PC;
d-DC7PC; d26-DC7PC;
Deuterated DHPC;
d-DHPC; d26-DHPC
Formula:
C22H18D26NO8P
Formula Weight: 507.7
Deuterium enrichment: ≥ 98% on all
heptanoic
acid positions, except 60-80%D on
alpha
*>99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (TLC, ESI-MS, 1H-NMR, 31P-NMR)
Citations of this product:
Mohamadi, M., Goricanec, D., Wagner, G., & Hagn, F. (2023). NMR sample optimization and backbone assignment of a stabilized neurotensin receptor. Journal of structural biology, 215(2), 107970.
O’Brien, E. S., Lin, D. W., Fuglestad, B., Stetz, M. A., Gosse, T., Tommos, C., & Wand, A. J. (2018). Improving yields of deuterated, methyl labeled protein by growing in H 2 O. Journal of biomolecular NMR, 71, 263-273.
DH7PC-d35
1,2-Diheptanoyl-d26-sn-glycero-3-phosphocholine-d9
Catalog # 0723
CAS # 39036-04-9 (unlabeled)
Synonyms:
d35-Diheptanoyllecithin;
1,2-dienanthioyl-d26-sn-glycero-3-phosphocholine-d9;
Dienanthioyl
phosphatidylcholine-d35;
7:0-d13 /
7:0-d13
PC -
d9; 7:0
PC-d35;
Deuterated
DH7PC;
d-DH7PC; d35-DH7PC;
Deuterated PC;
Deuterated D7PC;
d35-D7PC; d-D7PC;
Deuterated
DC7PC;
d-DC7PC; d35-DC7PC;
Deuterated DHPC;
d-DHPC; d35-DHPC
Formula:
C22H9D35NO8P
Formula Weight: 516.8
Deuterium enrichment: ≥ 98% on the
choline and
all heptanoic acid positions, except
50-70%D on
alpha
*>99%D available on request
Purity: 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
10-MAG-d24
1-Decanoyl-d19-rac-glycerol-d5
Catalog # 1321
CAS # 2277-23-8 (unlabeled)
Synonyms: Monocaprin-d24
Formula:
C13H2D24O4
Molecular Weight: 270.49
Deuterium enrichment: 98%
Purity: ≥ 99%
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
LDAO-d31
n-Dodecyl-d25-N,N-dimethyl-d6-N-oxide
Catalog # 1215
CAS # 1643-20-5 (unlabeled)
Synonyms: d31-Lauryldimethylamine-N-oxide;
N,N-Dimethyl-1-Dodecanamine-N-Oxide;
Deuterated LDAO; d-LDAO;
Perdeuterated LDAO; N,N-Dimethyldodecylamine N-oxide;
deuterated DDAO, d-DDAO; d-Lauryldimethylamine N-oxide
Formula:
C14D31NO
Formula Weight: 260.6
Deuterium enrichment: ≥ 98% * > 99 % D available on request
Purity: ≥ 99 %
Supplied as: solid
Storage: -20°C
Stability: ≥ 2 years
Data: (TLC, ESI-MS, 1H-NMR)
Citations of this product:
Günsel, U., Klöpfer, K., Häusler, E., Hitzenberger, M., Bölter, B., Sperl, L. E., ... & Hagn, F. (2023). Structural basis of metabolite transport by the chloroplast outer envelope channel OEP21. Nature Structural & Molecular Biology, 30(6), 761-769.
Eddy, M. T., Yu, T. Y., Wagner, G., & Griffin, R. G. (2019). Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR. Journal of biomolecular NMR, 73(8), 451-460.
Hiller, S., Malia, T. J., Garces, R. G., Orekhov, V. Y., & Wagner, G. (2010). Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1. Biomolecular NMR assignments, 4, 29-32.
Hiller, S., Ibraghimov, I., Wagner, G., & Orekhov, V. Y. (2009). Coupled decomposition of four-dimensional NOESY spectra. Journal of the American Chemical Society, 131(36), 12970-12978.
Bayrhuber, M., Maslennikov, I., Kwiatkowski, W., Sobol, A., Wierschem, C., Eichmann, C., ... & Riek, R. (2019). Nuclear magnetic resonance solution structure and functional behavior of the human proton channel. Biochemistry, 58(39), 4017-4027.
Yu, T. Y., Raschle, T., Hiller, S., & Wagner, G. (2012). Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs. Biochimica et Biophysica Acta (BBA)-Biomembranes, 1818(6), 1562-1569.
Hiller, S., Garces, R. G., Malia, T. J., Orekhov, V. Y., Colombini, M., & Wagner, G. (2008). Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Science, 321(5893), 1206-1210.
Böhm, R., Amodeo, G. F., Murlidaran, S., Chavali, S., Wagner, G., Winterhalter, M., ... & Hiller, S. (2020). The structural basis for low conductance in the membrane protein VDAC upon β-NADH binding and voltage gating. Structure, 28(2), 206-214.
γ-13CH3-d6-DL-Isoleucine.HCl
4-13C-4,5,5,5-d4-DL-Isoleucine hydrochloride
Catalog # 01IG4HCl
Synonyms: gama-13C-methyl labeled isoleucine; 13C-isoleucine; γ -13C-methyl labeled isoleucine
Formula: C513CH8D6ClNO2
Formula Weight: 174.7
This product is under development. The specifications below are not final.
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: 50% (racemic mixture of D- and L-isoleucine)
Purity: 95% (isoleucine)
Contains ≤ 5% allo-isoleucine
For bacterial and cell-free protein expression. Not tested for eukaryotic cell expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
γ-13CH3-d6-Isoleucine
4-13C-4,5,5,5-d4-DL-Isoleucine
Catalog # 01IG4HCl
Synonyms: gama-13C-methyl labeled isoleucine; 13C-isoleucine; γ -13C-methyl labeled isoleucine
Formula: C513CH7D6NO2
Formula Weight: 138.2
This product is under development. The specifications below are not final.
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: 50% (racemic mixture of D- and L-isoleucine)
Purity: 95% (isoleucine)
Contains ≤ 5% allo-isoleucine
Additionally purified by ion exchange chromatography and tested for mammalian and insect cell expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
Pro-R-13CH3-d4-Leucine.HCl
δ1-13CH3-d4-DL-Leucine hydrochloride
Catalog # 01LR4HCl
Synonyms: pro-R-13C-methyl-4,5,5,5-d4-DL-Leucine; δ1-13CH3-δ2-CD3-γ-d-Leucine; 13C-methyl labeled leucine; 13C-leucine; pro-R-methyl leucine
Formula: C513CH10D4ClNO2
Formula Weight: 172.7
Deuterium enrichment: ≥ 96% 13C enrichment: 99%
Optical Purity: 50% (racemic mixture of L-leucine and D-leucine)
Purity: 98% (Leucine)
Contains ≤10% of the pro-S isotopomer
For bacterial and cell-free protein expression.
Not tested for eukaryotic cell expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
Data: (1H-NMR ; 13C-NMR ; ESI-MS)
Citations of our product:
Dubey, A., Stoyanov, N., Viennet, T., Chhabra, S., Elter, S., Borggräfe, J., ... & Arthanari, H. (2021). Local deuteration enables NMR observation of methyl groups in proteins from eukaryotic and cell‐free expression systems. Angewandte Chemie International Edition, 60(25), 13783-13787.Mallis, R. J., Lee, J. J., Berg, A. V. D., Brazin, K. N., Viennet, T., Zmuda, J., ... & Arthanari, H. (2024). Efficient and economic protein labeling for NMR in mammalian expression systems: Application to a preT‐cell and T‐cell receptor protein. Protein Science, 33(4), e4950.
Pro-R-13CH3-d4-Leucine
δ1-13CH3-d4-DL-Leucine
Catalog # 01LR4cc
CAS # 760-84-9 (unlabeled, HCl
salt)
CAS # 61-90-5 (unlabeled,
zwitterion)
Synonyms:
pro-R-13C-methyl-4,5,5,5-d4-DL-Leucine;
δ1-13CH3-δ2-CD3-γ-d-Leucine;
13C-methyl labeled
leucine; 13C-leucine;
pro-R-methyl leucine
Formula:
C513CH9D4NO2
Formula Weight: 136.2
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: 50% (racemic mixture
of L-leucine and D-leucine)
Purity: 99% (Leucine)
Contains ≤10% of the pro-S
isotopomer
Additionally purified by ion
exchange chromatography and tested
for mammalian and insect cell
expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
1H-NMR spectrum
Citations of our product:
Dubey, A., Stoyanov, N., Viennet, T., Chhabra, S., Elter, S., Borggräfe, J., ... & Arthanari, H. (2021). Local deuteration enables NMR observation of methyl groups in proteins from eukaryotic and cell‐free expression systems. Angewandte Chemie International Edition, 60(25), 13783-13787.Mallis, R. J., Lee, J. J., Berg, A. V. D., Brazin, K. N., Viennet, T., Zmuda, J., ... & Arthanari, H. (2024). Efficient and economic protein labeling for NMR in mammalian expression systems: Application to a preT‐cell and T‐cell receptor protein. Protein Science, 33(4), e4950.
Pro-S-13CH3-d4-Leucine.HCl
δ2-13CH3-d4-DL-Leucine hydrochloride
Catalog # 01LS4HCl
Synonyms: pro-S-13C-methyl-4,5,5,5-d4-DL-Leucine; δ2-13CH3-δ1-CD3-γ-d-Leucine; 13C-methyl labeled leucine; 13C-leucine; pro-S-methyl leucine
Formula: C513CH10D4ClNO2
Formula Weight: 172.7
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: 50% (racemic mixture of L-leucine and D-leucine)
Purity: 98% (Leucine)
Contains ≤10% of the pro-R isotopomer
For bacterial and cell-free protein expression.
Not tested for eukaryotic cell expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
Data: (1H-NMR ; 13C-NMR ; ESI-MS)
Citations of our product:
Dubey, A., Stoyanov, N., Viennet, T., Chhabra, S., Elter, S., Borggräfe, J., ... & Arthanari, H. (2021). Local deuteration enables NMR observation of methyl groups in proteins from eukaryotic and cell‐free expression systems. Angewandte Chemie International Edition, 60(25), 13783-13787.Mallis, R. J., Lee, J. J., Berg, A. V. D., Brazin, K. N., Viennet, T., Zmuda, J., ... & Arthanari, H. (2024). Efficient and economic protein labeling for NMR in mammalian expression systems: Application to a preT‐cell and T‐cell receptor protein. Protein Science, 33(4), e4950.
Pro-S-13CH3-d4-Leucine
δ2-13CH3-d4-DL-Leucine
Catalog # 01LS4cc
CAS # 760-84-9 (unlabeled, HCl
salt)
CAS # 61-90-5 (unlabeled,
zwitterion)
Synonyms:
pro-S-13C-methyl-4,5,5,5-d4-DL-Leucine;
δ2-13CH3-δ1-CD3-γ-d-Leucine;
13C-methyl labeled
leucine; 13C-leucine;
pro-S-methyl leucine
Formula:
C513CH9D4NO2
Formula Weight: 136.2
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: 50% (racemic mixture
of L-leucine and D-leucine)
Purity: 99% (Leucine)
Contains ≤10% of the pro-R
isotopomer
Additionally purified by ion
exchange chromatography and tested
for mammalian and insect cell
expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
1H-NMR spectrum
Citations of our product:
Dubey, A., Stoyanov, N., Viennet, T., Chhabra, S., Elter, S., Borggräfe, J., ... & Arthanari, H. (2021). Local deuteration enables NMR observation of methyl groups in proteins from eukaryotic and cell‐free expression systems. Angewandte Chemie International Edition, 60(25), 13783-13787.Mallis, R. J., Lee, J. J., Berg, A. V. D., Brazin, K. N., Viennet, T., Zmuda, J., ... & Arthanari, H. (2024). Efficient and economic protein labeling for NMR in mammalian expression systems: Application to a preT‐cell and T‐cell receptor protein. Protein Science, 33(4), e4950.
Pro-R-13CH3-d6-Leucine.HCl
δ1-13CH3-d6-DL-Leucine hydrochloride
Catalog # 01LR6HCl
CAS # 760-84-9 (unlabeled, HCl
salt)
CAS # 61-90-5 (unlabeled,
zwitterion)
Synonyms:
pro-R-13C-methyl-3,3,4,5,5,5-d6-DL-Leucine;
δ1-13CH3-δ2-CD3-d3-Leucine;
13C-methyl labeled
leucine; 13C-leucine;
pro-R-methyl leucine
Formula:
C513CH8D6ClNO2
Formula Weight: 174.7
Deuterium enrichment: ≥ 96%
Optical Purity: 50% (racemic mixture
of L-leucine and D-leucine)
Purity: 98% (Leucine)
Contains ≤10% of the pro-S
isotopomer
For bacterial and cell-free protein
expression.
Not tested for
eukaryotic cell expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
1H-NMR spectrum
Pro-R-13CH3-d6-Leucine
δ1-13CH3-d6-DL-Leucine
Catalog # 01LR6cc
CAS # 760-84-9 (unlabeled, HCl
salt)
CAS # 61-90-5 (unlabeled,
zwitterion)
Synonyms:
pro-R-13C-methyl-3,3,4,5,5,5-d6-DL-Leucine;
δ1-13CH3-δ2-CD3-d3-Leucine;
13C-methyl labeled
leucine; 13C-leucine;
pro-R-methyl leucine
Formula:
C513CH7D7NO2
Formula Weight: 138.2
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: 50% (racemic mixture
of L-leucine and D-leucine)
Purity: 99% (Leucine)
Contains ≤10% of the pro-S
isotopomer
Additionally purified by ion
exchange chromatography and tested
for mammalian and insect cell
expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
1H-NMR spectrum
Pro-S-13CH3-d6-Leucine.HCl
δ2-13CH3-d6-DL-Leucine hydrochloride
Catalog # 01LS6HCl
CAS # 760-84-9 (unlabeled, HCl
salt)
CAS # 61-90-5 (unlabeled,
zwitterion)
Synonyms:
pro-S-13C-methyl-3,3,4,5,5,5-d6-DL-Leucine;
δ2-13CH3-δ1-CD3-d3-Leucine;
13C-methyl labeled
leucine; 13C-leucine;
pro-S-methyl leucine
Formula:
C513CH8D6ClNO2
Formula Weight: 174.7
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: 50% (racemic mixture
of L-leucine and D-leucine)
Purity: 98% (Leucine)
Contains ≤10% of the pro-R
isotopomer
For bacterial and cell-free protein
expression.
Not tested for
eukaryotic cell expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
1H-NMR spectrum
Pro-S-13CH3-d6-Leucine
δ2-13CH3-d6-DL-Leucine
Catalog # 01LS6cc
CAS # 760-84-9 (unlabeled, HCl
salt)
CAS # 61-90-5 (unlabeled,
zwitterion)
Synonyms:
pro-S-13C-methyl-3,3,4,5,5,5-d6-DL-Leucine;
δ2-13CH3-δ1-CD3-d3-Leucine;
13C-methyl labeled
leucine; 13C-leucine;
pro-S-methyl leucine
Formula:
C513CH7D6NO2
Formula Weight: 138.2
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: 50% (racemic mixture
of L-leucine and D-leucine)
Purity: 99% (Leucine)
Contains ≤10% of the pro-R
isotopomer
Additionally purified by ion
exchange chromatography and tested
for mammalian and insect cell
expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
1H-NMR spectrum
4-13C-Fluorophenylalanine-d2.HCl
4-13C-3,5-d2-L-4-Fluorophenylalanine hydrochloride
Catalog # 01FFd2HCl
CAS # 1132-68-9 (unlabeled, zwitterion)
CAS # 64231-54-5 (unlabeled, HCl salt)
Synonyms:13C-fluorophenylalanine;
13C-L-fluorophenylalanine; 13C-4F-Phe;
13C-L-p-Fluorophenylalanine;
13C-p-Fluoro-L-phenylalanine;
ring-4-13C-4-Fluoro-L-phenylalanine
Formula:
C813CH9D2ClFNO2
Formula Weight: 222.6
Deuterium enrichment: ≥ 96%
13C enrichment: 98%
Purity: 95%
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
This product is distributed by Cambridge Isotope
Laboratories, Inc.
Data: (1H-NMR, 13C-NMR, 19F-NMR)
4-13C-Phenylalanine-d2.HCl
4-13C-3,5-d2-L-Phenylalanine hydrochloride
Catalog # 01PheD2HCl
CAS # 63-91-2 (unlabeled, zwitterion)
CAS # 17585-69-2 (unlabeled, HCl salt)
Synonyms:L-phenylalanine, 13C-phenylalanine;
13C-Phe; 13C-labeled Phe
Formula:
C813CH10D2ClFNO2
Formula Weight: 204.7
Deuterium enrichment: ≥ 96%
13C enrichment: 98%
Purity: 95% *
*For bacterial and cell-free protein expression.
Please inquire about insect and mammalian cell expression.
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
Data:
1H-NMR spectrum
13C-NMR spectrum
Pro-R-13CH3-d4-L-Valine.HCl
γ1-13CH3-d4-L-Valine hydrochloride
Catalog # 01VR4HCl
Synonyms: pro-R-13C-methyl-3,4,4,4-d4-L-Valine; γ1-13CH3-γ2-CD3-β-d-Valine; 13C-methyl labeled valine; 13C-valine; pro-R-methyl valine
Formula: C413CH8D4ClNO2
Formula Weight: 158.6
This product is under development. The specifications below are not final.
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: ≥ 90%
Purity: 98% (Valine)
Contains ≤10% of the pro-S isotopomer
For bacterial and cell-free protein expression.
Not tested for eukaryotic cell expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
Pro-R-13CH3-d4-L-Valine
γ1-13CH3-d4-L-Valine
Catalog # 01VR4cc
Synonyms: pro-R-13C-methyl-3,4,4,4-d4-L-Valine; γ1-13CH3-γ2-CD3-β-d-Valine; 13C-methyl labeled valine; 13C-valine; pro-R-methyl valine
Formula: C413CH7D4NO2
Formula Weight: 122.2
This product is under development. The specifications below are not final.
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: ≥ 90%
Purity: 99% (Valine)
Contains ≤10% of the pro-S isotopomer
Additionally purified by ion exchange chromatography and tested for mammalian and insect cell expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
Pro-S-13CH3-d4-L-Valine.HCl
γ2-13CH3-d4-L-Valine hydrochloride
Catalog # 01VS4HCl
Synonyms: pro-S-13C-methyl-3,4,4,4-d4-L-Valine; γ2-13CH3-γ1-CD3-β-d-Valine; 13C-methyl labeled valine; 13C-valine; pro-S-methyl valine
Formula: C413CH8D4ClNO2
Formula Weight: 158.6
This product is under development. The specifications below are not final.
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: ≥ 90%
Purity: 98% (Valine)
Contains ≤10% of the pro-R isotopomer
For bacterial and cell-free protein expression.
Not tested for eukaryotic cell expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
Pro-S-13CH3-d4-L-Valine
γ2-13CH3-d4-L-Valine
Catalog # 01VS4cc
Synonyms: pro-S-13C-methyl-3,4,4,4-d4-L-Valine; γ2-13CH3-γ1-CD3-β-d-Valine; 13C-methyl labeled valine; 13C-valine; pro-S-methyl valine
Formula: C413CH7D4NO2
Formula Weight: 122.2
This product is under development. The specifications below are not final.
Deuterium enrichment: ≥ 96%
13C enrichment: 99%
Optical Purity: ≥ 90%
Purity: 99% (Valine)
Contains ≤10% of the pro-R isotopomer
Additionally purified by ion exchange chromatography and tested for mammalian and insect cell expression
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
5-13C-Fluorouracil
2,4-Dihydroxy-5-fluoropyrimidine-5-13C
Catalog # 01FU5C
CAS # 51-21-8 (unlabeled)
Synonyms: 5-13C-5-FU,
5-13C-5-Fluoro-2,4(1H,3H)-pyrimidinedione;
13C-labeled fluorouracil
Formula:
C313CH3FN2O2
Formula Weight: 131.7
13C enrichment: 98%
Purity: 95%
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
5-13C-uracil
2,4-Dihydroxypyrimidine-5-13C
Catalog # 01U5C
CAS # 66-22-8 (unlabeled)
Synonyms: 5-13C-U,
5-13C-2,4(1H,3H)-pyrimidinedione;
13C-labeled uracil
Formula:
C313CH4N2O2
Formula Weight: 113.1
13C enrichment: 98%
Purity: 95%
Supplied as: solid
Storage: room temperature
Stability: ≥ 2 years
In order to expand our catalog, we offer reasonable prices for custom synthesis of new compounds.
About Us
Every chemist dreams of seeing molecules. Frankenstein Bio Reagents began around 2002 in Cambridge (MA) when Vlado Gelev, a chemist among biophysicists, started supplying his friends with 13C-methyl amino acid precursors. These compounds allowed cleaner observation of the motions and interactions of large proteins by nuclear magnetic resonance. The company was registered as a DBA in 2009 and expanded into the manufacture of high purity deuterated detergents and lipids for the study of membrane proteins. In 2014 the company relocated to Dr. Gelev's hometown of Sofia, Bulgaria, where he was offered a faculty position at Sofia University Faculty of Chemistry and Pharmacy. The company employs the expertise of undergraduate and graduate students and faculty, while continuing to collaborate internationally. In 2019 we were proud to be part of a multidisciplinary team reporting the utility of aromatic 13C-19F pairs to produce remarkably sharp NMR signals. In 2021 our team reported the use of "locally deuterated" and methyl-13C leucine in cell-free and insect cell culture.
FB Reagents now offer the largest selection of deuterated phospholipids and detergents, as well as 13C-1H and 13C-19F labeled compounds. Our products are distributed by Cambridge Isotope Laboratories (USA), Larodan (Sweden), Cortecnet (France) and others. Whether you look at molecules through magnetic resonance, neutron scattering, Raman spectroscopy or another technique, we help you see what you want to see.
See LINKS for a list of research publications using our products.
Links
Research publications using our products
Hiller, S., Garces, R. G., Malia, T. J., Orekhov, V. Y., Colombini, M., & Wagner, G. (2008). Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Science, 321(5893), 1206-1210. Hiller, S., Ibraghimov, I., Wagner, G., & Orekhov, V. Y. (2...
Basics of Protein NMR
Seeing Molecules
With Nuclear Magnetic Resonance
AI Gibberish
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